Interventions for prudent antibiotic use in primary healthcare: an econometric analysis

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(2020) 20:895

RESEARCH ARTICLE

Open Access

Interventions for prudent antibiotic use in primary healthcare: an econometric analysis Elina Lampi1,2†, Fredrik Carlsson1,2†, Pär-Daniel Sundvall3,4, Marcela Jaime Torres5, Peter Ulleryd6,7, Christina Åhrén2,7,8 and Gunnar Jacobsson2,7,8,9*

Abstract Background: Rational antibiotic prescribing is crucial to combat antibiotic resistance. Optimal strategies to improve antibiotic use are not known. Strama, the Swedish strategic program against antibiotic resistance, has been successful in reducing antibiotic prescription rates. This study investigates whether two specific interventions directed toward healthcare centers, an informational visit and a self-evaluation meeting, played a role in observed reduction in rates of antibiotic prescriptions in primary healthcare. Methods: The study was a retrospective, observational, empirical analysis exploiting the variation in the timing of the interventions and considering past prescriptions through use of estimations from dynamic panel data models. Primary healthcare data from 2011 to 2014 were examined. Data were from public and private primary healthcare centers in western Sweden. The key variables were prescription of antibiotics and indicator variables for the two interventions. Results: The first intervention, an educational information intervention, decreased the number of prescriptions among public healthcare centers, but this effect was only temporary. We found no proof that the second intervention, a self-evaluation meeting at the healthcare center, had an impact on the reduction of prescriptions. Conclusions: Single educational interventions aimed at influencing rates of antibiotic prescriptions have limited impact. A multifaceted approach is needed in efforts to reduce the use of antibiotics in primary health care. Keywords: Health services research, Primary healthcare, Quality improvement, Antibiotics, Intervention, Selfevaluation

* Correspondence: [email protected] † Elina Lampi and Fredrik Carlsson contributed equally to this work. 2 Center for Antibiotic Resistance Research (CARe), University of Gothenburg, Guldhedsgatan 10, 405 30 Gothenburg, SE, Sweden 7 Swedish Strategic Program against Antimicrobial Resistance (Strama), Region Västra Götaland, Bergslagsgatan 2, SE-411 04 Gothenburg, Sweden Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is