Intracranial Germ Cell Tumors
Intracranial germ cell tumors are a group of uncommon neoplasms of the central nervous system. The clinical features and natural history of these lesions are quite unique and variable. While intracranial germ cell tumors have been a fascination to neuroon
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SpringerWienNewYork
Prof. Dr. Yutaka Sawamura
Department of Neurosurgery, Hokkaido University School of Medicine, Sapporo, Japan
Prof. Dr. Hiroki Shirato Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
Prof. Dr. Nicolas de Tribolet Service de Neurochirurgie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
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© 1998 Springer-Verlag/Wien Softcover reprint of the hardcover 1st edition 1998 Typesetting: Thomson Press (India) Ltd., New Delhi 110001 Cover design: B. Kollmann Printed on acid-free and chlorine-free bleached paper SPIN: 10636617
With 111 partly coloured Figures
Library of Congress Cataloging-in-Publication Data Intracranial germ cell tumors 1 Yutaka Sawamura, Hiroki Shirato, Nicolas de Tribolet (eds.). p. cm. Includes bibliographical references. ISBN-13: 978-3-7091-7414-2 e-ISBN-13: 978-3-7091-6821-9 DOl: 10.1007/978-3-7091-6821-9 1. Brain-Tumors. 2. Pineal gland-Tumors. 3. Germ cellsTumors. I. Sawamura, Yutaka. II. Shirato, Hiroki. III. Tribolet, Nicolas de. [DNLM: 1. Brain Neoplasms-therapy. 2. Brain Neoplasmsdiagnosis. 3. Germinoma-therapy. 4. Germinoma-diagnosis. 5. Teratoma-therapy. 6. Teratoma-diagnosis. WL 358162 1998] RC280.B7I58 1998 616.99'481-dc21 DNLMIDL.C for Library of Congress 98-21794 CIP
Foreword Intracranial germ cell tumors are a group of relatively uncommon neoplasms of the central nervous system. The presenting signs and symptoms, histopathology, radiographic appearance, response to therapy, and natural history of these lesions are quite unique and variable. While intracranial germ cell tumors have been a fascination to neuro-oncologist for decades, the relatively small number of patients seen in any single institution has hampered the important clinical investigation that is so needed. More recently through the establishment of multi-institutional trials, important lessons are being learned concerning the optimization of therapy. This textbook co-edited by Drs. Sawamura, Shirato, and de Tribolet provides an outstanding reference source for physicians taking care of patients with intracranial germ cell tumors. It is very apparent that the incidence of this disease is far greater in Japan than in the United States and in Europe. The existence of the Japan Brain Tumor Regi
