Intragastric Balloon Versus Endoscopic Sleeve Gastroplasty for the Treatment of Obesity: a Systematic Review and Meta-an
- PDF / 2,970,854 Bytes
- 20 Pages / 595.276 x 790.866 pts Page_size
- 48 Downloads / 195 Views
ORIGINAL CONTRIBUTIONS
Intragastric Balloon Versus Endoscopic Sleeve Gastroplasty for the Treatment of Obesity: a Systematic Review and Meta-analysis Shailendra Singh 1 & Diogo Turiani Hourneaux de Moura 2 & Ahmad Khan 3 & Mohammad Bilal 4 & Monica Chowdhry 3 & Michele B. Ryan 2 & Ahmad Najdat Bazarbashi 2 & Christopher C. Thompson 2
# Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Background We aimed to individually evaluate IGB and ESG procedures and compare the efficacy, durability, and safety of these procedures. Methods Bibliographic databases were systematically searched for studies investigating the use of IGB and ESG for the treatment of obesity. Studies reporting percent total weight loss (%TWL) or percent excess weight loss (%EWL) with at least 12 months of follow-up were included. Results A total of 28 studies were included in the final analysis. Only 1 study directly compared ESG to IGB, 9 studies evaluated ESG alone, while 18 studies evaluated IGB. At 12-month follow-up after ESG, mean %TWL was 17.51 (95% CI 16.44–18.58), and %EWL was 60.51 (95% CI 54.39–66.64). Mean %TWL and %EWL after IGB at 12 months was 10.35 (95% CI 8.38–12.32) and 29.65 (95% CI 25.40–33.91), respectively. Mean %TWL and %EWL after IGB were significantly decreased at 18 or 24 months compared to 6 months indicating weight regain after IGB removal. ESG achieved significantly superior weight loss compared to IGB, the difference in mean %TWL was 7.33 (95% CI 5.22–9.44, p value = 0.0001) at 12 months. Serious adverse events were observed in < 5% for both procedures. Conclusion Although ESG and IGB are safe and effective for weight loss, our study suggests that ESG results in more significant and sustained weight loss. Nevertheless, a variety of approaches are essential to care for this underserved population, and there are several factors other than weight loss that should be considered in selecting the ideal therapy for individual patients. Keywords Obesity . Intragastric balloon . Gastric balloon . IGB . Endoscopic sleeve gastroplasty . ESG . Endoscopic and bariatric therapy Electronic supplementary material The online version of this article (https://doi.org/10.1007/s11695-020-04644-8) contains supplementary material, which is available to authorized users. * Shailendra Singh [email protected]
Ahmad Najdat Bazarbashi [email protected] Christopher C. Thompson [email protected]
Diogo Turiani Hourneaux de Moura [email protected] Ahmad Khan [email protected]
1
Division of Gastroenterology, West Virginia University Health Sciences Center Charleston Division, Charleston, WV, USA
Mohammad Bilal [email protected]
2
Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Monica Chowdhry [email protected]
3
Department of Medicine, West Virginia University Health Sciences Center Charleston Division, Charleston, WV, USA
Michele B. Ryan [email protected]
4
Division of Gastroenterology, Beth Israe
Data Loading...
