Introduction to Statistical Methods in Pathology
This text provides a comprehensive and practical review of the main statistical methods in pathology and laboratory medicine. It introduces statistical concepts used in pathology and laboratory medicine. The information provided is relevant to pathologist
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Amir Momeni Matthew Pincus Jenny Libien
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Introduction to Statistical Methods in Pathology
Amir Momeni • Matthew Pincus Jenny Libien
Introduction to Statistical Methods in Pathology
Amir Momeni Department of Pathology State University of New York Downstate Medical Center Brooklyn, New York, USA
Matthew Pincus Department of Pathology State University of New York Downstate Medical Center Brooklyn, New York, USA
Jenny Libien Department of Pathology State University of New York Downstate Medical Center Brooklyn, New York, USA
ISBN 978-3-319-60542-5 ISBN 978-3-319-60543-2 DOI 10.1007/978-3-319-60543-2
(eBook)
Library of Congress Control Number: 2017944203 # Springer International Publishing AG 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
To an ever-increasing extent, pathologists are being required to use statistics in their practice. In clinical pathology or laboratory medicine, statistics are a fundamental requirement for the evaluation of the reliability of quantitative results for values of serum and, in general, body fluid analytes such as electrolytes, glucose, blood urea nitrogen (BUN), creatinine, critical enzymes, etc. and for the analysis of the correlation between the results generated on different analyzers, all of which are used for quantitative determination of the same analytes. Correlations between measurements of parameters that allow categorization of tumors such as correlation of nuclear grade with pathological stage require knowledge of statistical methods in anatomic pathology. Correlation of the staging of different cancers with survival involves another major use of statistics in both anatomi
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