• PDF / 141,907 Bytes
• 1 Pages / 595.245 x 841.846 pts (A4) Page_size
• 68 Downloads / 158 Views

DOWNLOAD

REPORT

---

1

S

Small bowel angioedema: 4 case reports Four patients developed small bowel angioedema when they received IV iohexol or iopamidol during screening CT scan [times to reaction onset not clearly stated]. Patient 1, a 46-year-old man who had reflux oesophagitis, drank barium sulfate suspension about 30 minutes prior to abdominal CT scan, and another 150mL just prior to the procedure. An abdominopelvic CT scan was performed after he received iohexol [Omnipaque 300] at 3 mL/s via an automated injector [dose not stated]. He subsequently experienced sneezing, nasal obstruction and vomiting, for which he received fluids and an antihistamine injection. CT results revealed circumferential thickening of the jejunal walls. A small bowel follow-through study and repeat scan at 1 and 10 months, respectively, showed no abnormalities. Patients 2 and 3 underwent abdominopelvic CT scan using the same protocol as Patient 1. Patient 2, who was a 49-yearold man with erosive gastritis and colonic polyps, developed adverse GI symptoms and vomiting during the scan, but was discharged following hydration and observation. Patient 3 was a 57-year-old man with intestinal metaplasia who developed vomiting and similar GI symptoms as Patient 2. In both patients, CT scan showed circumferential thickening of the walls of the jejunum (Patient 3 also had thickened duodenal walls). Follow-up scans after 3 months showed normal bowel loops. Patient 4, a 48-year-old man with asthma and gastritis. He received IV iopamidol [Iopamiro 300] 150mL at 3 mL/s prior to an abdominopelvic CT scan and developed GI symptoms, including vomiting. Scan results showed circumferential thickening of the duodenal and jejunal walls. He was treated with fluids. Three months later, a repeat CT scan was normal. Author comment: "These findings suggest that their transient allergic reactions were due to contrast media in the small bowel." PARK SW, et al. Small-bowel angioedema during screening computed tomography due to intravenous contrast material. Journal of Computer Assisted Tomography 35: 549-552, No. 5, Sep-Oct 2011. Available from: URL: http:// 803062880 dx.doi.org/10.1097/rct.0b013e318224247e - South Korea

0114-9954/10/1378-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

Reactions 19 Nov 2011 No. 1378