Ionic liquids in whole-cell biocatalysis: a compromise between toxicity and efficiency
- PDF / 1,417,599 Bytes
- 20 Pages / 595.276 x 790.866 pts Page_size
- 98 Downloads / 166 Views
REVIEW
Ionic liquids in whole-cell biocatalysis: a compromise between toxicity and efficiency Ksenia S. Egorova 1 & Valentine P. Ananikov 1 Received: 9 October 2017 / Accepted: 13 December 2017 / Published online: 8 January 2018 # International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag GmbH Germany, part of Springer Nature 2018
Abstract Comparison of chemical catalysis by metal complexes, enzymatic catalysis and whole-cell biocatalysis shows well-addressed advantages of the latter approach. However, a critical limitation in the practical applications originates from the high sensitivity of microorganisms to the toxic effects of organic solvents. In the present review, we consider toxic solvent properties of ionic liquid/ water systems towards the development of efficient applications in practical organic transformations. Keywords Ionic liquids . Toxicity . Biological activity . Catalysis . Biocatalysis
Abbreviations AMMOENG™ Cocosalkylpenthaethoxymethylammonium 100 methylsulfate IL cations [CnMIM] [HOC2MIM] [CnC1MIM] [PPMIM] [AMIM] [BzMIM] [HOOC2MIM] [CnPy] [CnMPy] [CnMPyr] [CnMPip] [(C1OC3)C1Pip] [CnCnCnCnN] [Chol]
1-alkyl-3-methylimidazolium (2-hydroxy)ethyl-3methylimidazolium 1-alkyl-2,3-dimethylimidazolium 1-phenylpropyl-3-methylimidazolium 1-allyl-3-methylimidazolium 1-benzyl-3-methylimidazolium 1-carboxymethyl-3methylimidazolium N-alkylpyridinium N-alkyl-3-methyl-pyridinium N-alkyl-N-methylpyrrolidinium N-alkyl-N-methylpiperidinium N-methyl-N-(1-methoxypropyl)piperidinium N,N,N,N-tetraalkylammonium cholinium, N-(2-hydroxy)ethylN,N,N-trimethylammonium
This article is part of a Special Issue on ‘Ionic Liquids and Biomolecules’ edited by Antonio Benedetto and Hans-Joachim Galla. * Valentine P. Ananikov [email protected] 1
Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt 47, Moscow 119991, Russia
[(HOC2)(C1)2N]
N,N-dimethyl-N-ethanolammonium
[(HOC2)2C4C2N]
N,N-di(2-hydroxy)ethyl- N-butyl-Nethylammonium N-(3-hydroxy)propyl- N-ethyl-N,Ndimethylammonium N-(3-hydroxy)propyl- N-butyl-N,Ndimethylammonium Tris(2-hydroxyethyl)methylammonium Tetraalkylphosphonium Decyltris(3hydroxypropyl)phosphonium N,N,N’,N’-tetramethyl-N^ethylguanidinium PEG-5 cocomonium
[(HOC3)C2(C1)2N] [(HOC3)C4(C1)2N] [(HOC2)3C1N] [CnCnCnCnN] [(HOC3)3C10P] [(C1)4C2Gua] [CABHEM] IL anions [BF4] [PF6] [OTf] [NTf2] [(C2F5)3PF3] [N(CN)2] [SCN] [NO3] [OAc] [C2COO] [C5COO] [C1PO3] [C2PO4] [i-(C8)2PO4]
Tetrafluoroborate Hexafluorophosphate Trifluoromethanesulfonate Bis(trifluoromethylsulfonyl)imide Tris(pentafluoroethyl)trifluorophosphate Dicyanamide Thiocyanate Nitrate Acetate Propanoate Hexanoate Methylphosphonate Dimethylphosphate Bis(2,4,4-trimethylpentyl)phosphinate
882
[C2SO3] [CnSO4] [CnOCnSO4] [C1(OC2)3SO4] [Tos] [MDEGSO4] [SbF6] [Lac] [Sacch] [Doc] [Lin]
Biophys Rev (2018) 10:881–900
Ethylsulfonate Alkylsulfate 2-alkoxyalkylsulfate 2-[2-(2methoxy)ethoxy]ethoxyethylsulfate Tosylate, p-toluenesulfonate Ethylenglycolmonomethylethersulfate Hexafluoroantimonate Lactate Saccharinat
Data Loading...
