Journal Watch
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Mol Diag Ther 2008; 12 (2): 125-129 1177-1062/08/0002-0125/$48.00/0 © 2008 Adis Data Information BV. All rights reserved.
Journal Watch† Contents 1. Molecularly Targeted Therapies for Pediatric Acute Myeloid Leukemia: Progress to Date . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 2. Biomarker Analysis as a Decision-Making Tool in Drug Discovery and Development: Implications for Peroxisome ProliferatorActivator Receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 3. Diagnosis and Treatment of Giant Cell Arteritis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126 4. Clinical Features, Differential Diagnosis and Treatment of Autoimmune Hepatitis in the Elderly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126 5. Mitochondrial Dysfunction as the Molecular Basis of Bipolar Disorder: Therapeutic Implications . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126 6. The Role of Pharmacogenetics in the Metabolism of Antiepileptic Drugs: Pharmacokinetic and Therapeutic Implications . . . . 127 7. Genetic Forms of Primary Aldosteronism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127 8. Novel Genetic Techniques and Approaches in the Microbial Genomics Era: Identification and/or Validation of Targets for the Discovery of New Antibacterial Agents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128 9. EGFR, HER2 and VEGF Pathways: Validated Targets for Cancer Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128 10. Treatment of Acute Lymphoblastic Leukemia: A New Era . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128 11. Adult-Onset Still’s Disease: Pathogenesis, Clinical Manifestations and Therapeutic Advances . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128 12. Molecular Mechanisms Responsible for the Anti-Inflammatory and Protective Effect of High-Density Lipoprotein on the Endothelium . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 13. Genetic Polymorphisms in an Aged Population: Comparisons with a Large Population of Subjects and with Young Survivors of Myocardial Infarction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129
1. Molecularly Targeted Therapies for Pediatric Acute Myeloid
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