Laparoscopic Sleeve Gastrectomy Affects Coagulation System of Obese Patients
- PDF / 298,125 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 34 Downloads / 209 Views
ORIGINAL CONTRIBUTIONS
Laparoscopic Sleeve Gastrectomy Affects Coagulation System of Obese Patients Chen Liu 1 & Ziliang Han 1 & Nengwei Zhang 1 & Jirun Peng 1 & Bin Zhu 1 & Buhe Amin 1 & Dexiao Du 1 & Wei Yan 1 & Dongdong Zhang 1 & Ke Gong 1 Received: 9 October 2019 / Revised: 2 June 2020 / Accepted: 4 June 2020 # Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Background Laparoscopic sleeve gastrectomy (LSG) is nowadays the most popular bariatric procedure for obesity. However, whether LSG increases the risk of thrombosis remains unclear. The aim of this study was to investigate potential effects of LSG on coagulation system. Methods Fifty-five obese patients underwent LSG between 2016 and 2018. The LSG was performed with pneumoperitoneum pressure maintained at 13 mmHg. Venous blood specimens were collected from each patient before surgery, at the end of pneumoperitoneum (i.e., 0 h after surgery), and at 24 h after surgery to determine prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), platelet count (PLT), D-dimer (D-D), red blood cell count (RBC), hematocrit (HCT), plateletcrit (PCT), cholesterol (CHOL), triglyceride (TRIG), and serum calcium (Ca). All patients were examined on the veins of the lower limbs by color Duplex sonography (CDS) before surgery and at 24 h after surgery, respectively. Results All patients successfully underwent LSG. No severe surgery-related complications were observed during 1-month follow-up after operation. Preoperative BMI was 43.6 ± 8.3 kg/m2. The levels of coagulation factors were within the normal range before surgery, except a relatively higher PLT. The PT and D-D were increased at 0 h and 24 h after surgery (P < 0.05), whereas APTT was decreased (P < 0.05). The postoperative FIB remained similar to the preoperative one (P > 0.05). The CDS identified no thrombus in the veins of the lower limbs, either before surgery or at 24 h after surgery. Conclusions LSG may cause postoperative hypercoagulability of patients with obesity. Keywords Obesity . Laparoscopic sleeve gastrectomy . Coagulation system
Introduction Obesity is considered as a global epidemic disorder. In the last several decades, the incidence of obesity has been at least
doubled throughout the world. Obesity has become more and more prevalent among young adults [1]. As bariatric surgery is the only effective treatment for morbid obesity [2, 3], the number of procedures is growing rapidly in recent years.
* Ke Gong [email protected]
Buhe Amin [email protected]
Chen Liu [email protected]
Dexiao Du [email protected]
Ziliang Han [email protected]
Wei Yan [email protected]
Nengwei Zhang [email protected]
Dongdong Zhang [email protected]
Jirun Peng [email protected] Bin Zhu [email protected]
1
Department of General Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China
OBES SURG
In 2016, 685,874 bariatric procedures were performed worldwide [4]. In recent 10 years, China has witnessed a substantially
Data Loading...
