Late Effects in Children and Adolescents with Neuroblastoma

In 2016, approximately 2400 neuroblastoma patients in Germany had survived ≥10 years after diagnosis. The late sequelae follow-up programs should be tailored based on the highly divergent biology of low-risk and high-risk disease, the related treatment in

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123

Late Treatment Effects and Cancer Survivor Care in the Young

Jörn D. Beck  •  Carsten Bokemeyer Thorsten Langer Editors

Late Treatment Effects and Cancer Survivor Care in the Young From Childhood to Early Adulthood

Editors Jörn D. Beck Pediatric Hematology and Oncology University Hospital for Children and Adolescents Erlangen Germany

Carsten Bokemeyer Department of Onkology University Hospital Hamburg-Eppendorf Hamburg Germany

Thorsten Langer Pediatric Oncology and Hematology – Long-Term Follow-Up after Childhood Cancer University Hospital for Children and Adolescents Lübeck Germany

ISBN 978-3-030-49138-3    ISBN 978-3-030-49140-6 (eBook) https://doi.org/10.1007/978-3-030-49140-6 © Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

Part I Causes and Course of Severe Late Effects 1 Cardiotoxicity After Childhood Cancer Treatment����������������������   3 Kelley K. Hutchins, Rudolf Steiner, Emma R. Lipshultz, Stephen E. Sallan, and Steven E. Lipshultz 2 Kidney Disease in Childhood Cancer Survivors ��������������������������  17 Roderick Skinner and Lars Hjorth 3 Ototoxicity After Childhood Cancer����������������������������������������������  27 Amélie Tillmanns, Claudia Lanvers-Kaminsky, Ross Parfitt, Annelot Meijer, Miklós Tóth, Adrian Münscher, Jörn D. Beck, Marry van den Heuvel-Eibrink, and Antoinette am Zehnhoff-Dinnesen 4 Complications in Tumour Orthopaedics����������������������������������������  49 Jendrik Hardes and Arne Streitbürger 5 Causes and Course of Severe Late Effects in Young Cancer Patients: Gastrointestinal Tract������������������������������������������������������  57 Alexander Stein 6 Pulmonary