LAUDES Study: impact of digital ulcers on hand functional limitation, work productivity and daily activities, in systemi
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Rheumatology International https://doi.org/10.1007/s00296-019-04436-z
INTERNATIONAL
OBSERVATIONAL RESEARCH
LAUDES Study: impact of digital ulcers on hand functional limitation, work productivity and daily activities, in systemic sclerosis patients Ivan Castellví1 · Saioa Eguiluz2 · Alejandro Escudero‑Contreras3 · Juan José Ríos4 · Jaime Calvo‑Alén5 · José Luis Callejas‑Rubio6 · Carlos De la Puente7 · Carmen Pilar Simeón8 · Francisco Javier Narváez9 · Gerard Espinosa10 · Patricia E. Carreira11 · Manuel Rubio‑Rivas12 · Juan José Alegre13 · Alfredo Guillén‑Del‑Castillo8 · Jose Andrés Román‑Ivorra14 · Vicent Fonollosa8 on behalf of LAUDES Study Group Received: 8 July 2019 / Accepted: 24 August 2019 © Springer-Verlag GmbH Germany, part of Springer Nature 2019
Abstract The objective of this study was to evaluate the impact of digital ulcers (DUs) in daily life of systemic sclerosis (SSc) Spanish patients. We developed a multicenter observational study to compare functional disability in SSc patients with active DUs vs. those without DUs. An additional correlation between perception of patients and physicians on disability due to DUs was performed. A total of 199 patients were enrolled, 70 (35%) with DUs. Patients with DUs were younger (48 vs. 58 years; p
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