Lectins
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Large Cell Medulloblastoma Definition Large cell medulloblastoma is a recently acknowledged variant of medulloblastoma, accounting for approximately 4% of cases. It is characterized by more abundant cytoplasm than seen in classic medulloblastoma and large areas of necrosis.
Large Dense Core Vesicles Definition Large dense core vesicles (LDCVs) are electron dense granules of neurons and neuroendocrine cells with a diameter ranging from 80 to 400 nm. The dense matrix contains granins, neuropeptides and hormones, the membrane cytochrome b561 and dopamine-b hydroxylase.
Laryngeal Carcinoma, genetic changes Charlotte Jin Department of Clinical Genentics, University Hospital, Lund, Sweden [email protected]
Definition The vast majority of malignant neoplasms of the larynx arise from the surface epithelium and are therefore classified as keratinizing or non-keratinizing squamous cell carcinomas (SCC). The other rare malignant forms include verrucous carcinoma, adenocarcinoma, fibrosarcoma and chondrosarcoma. Histopathologically, laryngeal SCC can further be classified into: well differentiated (more than 75% keratinization), moderately differentiated (25 ± 75% keratinization), poorly differentiated (
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