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Left‑sided infective endocarditis in persons who inject drugs Glen Huang1 · Kyle A. Davis4 · S. Allan Petty2 · Walter A. Tan1,2 · Erin W. Barnes1,3 · James E. Peacock Jr.1,3 Received: 24 October 2019 / Accepted: 8 February 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose  The purpose of this study was to describe left-sided infective endocarditis (LSIE) in persons who inject drugs (PWID) and compare that group to PWID with non-LSIE and to non-PWID with LSIE. Methods  Retrospective single-center study of adult IE patients from 2011 to 2018. Results  Of the 333 patients in our cohort, 54 were PWID with LSIE, 75 were PWID with non-LSIE, and 204 were non-PWID with LSIE. When comparing LSIE vs non-LSIE in PWID, the LSIE group was older (median age 35 vs 28.5, p 

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