Left ventricular mechanical dyssynchrony analzyed by Tc-99m sestamibi SPECT and F-18 FDG PET in patients with ischemic c
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ORIGINAL PAPER
Left ventricular mechanical dyssynchrony analzyed by Tc‑99m sestamibi SPECT and F‑18 FDG PET in patients with ischemic cardiomyopathy and the prognostic value Yi Tian1 · Min Zhao2 · Weilong Li3 · Ziwei Zhu1 · Hongzhi Mi1 · Xiang Li4 · Xiaoli Zhang1 Received: 28 March 2020 / Accepted: 29 May 2020 © Springer Nature B.V. 2020
Abstract To compare the left ventricular (LV) phase dyssynchrony parameters obtained from Tc-99m Sestamibi SPECT (GSPECT) and F-18 FDG PET(GPET), as well as the prognostic values in patients with ischemic cardiomyopathy (ICM). Consecutive ICM patients referred for myocardial viability assessment were retrospectively evaluated and were followed-up for 21 ± 5 months. Phase parameter from both GSPECT and GPET were analyzed by QGS software, including histogram bandwidth (BW), standard deviation (SD) and entropy. Independent predictor for cardiac death was analyzed by Cox regression analysis. The estimated cardiac survival curve was analyzed by and was compared with the log-rank test. Eight-eight (mean age 56 ± 10, male 94%, L VEFSPECT23 ± 10%) ICM patients were included for analysis. Moderate correlations were observed for BW (r = 0.65; p
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