Left ventricular mechanics in patients with hematological malignancies before initiation of chemo- and radiotherapy
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ORIGINAL PAPER
Left ventricular mechanics in patients with hematological malignancies before initiation of chemo‑ and radiotherapy Milan Pavlovic1 · Aleksandar Dordevic1 · Sabine Haßfeld1 · Cesare Cuspidi2,3 · Hans‑Dirk Düngen1 · Marijana Tadic1 Received: 23 August 2020 / Accepted: 5 October 2020 © Springer Nature B.V. 2020
Abstract ObjectiveWe sought to investigate left ventricular (LV) structure, function and mechanics in the patients with leukemia and lymphoma before initiation of chemotherapy, as well as the relationship between hematological malignancies and reduced LV longitudinal strain.MethodsThis retrospective investigation included 71 patients with leukemia and lymphoma before chemotherapy and 36 healthy controls. All participants underwent echocardiographic examination before initiation of chemotherapy and radiotherapy.ResultsLV global longitudinal strain (− 20.2 ± 1.7% vs. − 17.9 ± 3.0%, p
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