Lichen Secondary Metabolites Bioactive Properties and Pharmaceutical

This revised and extended edition provides in-depth insights into the benefits and untapped potential of lichen-derived bioactive compounds. The whole spectrum of these compounds’ biological and medical functions, from antibiotic to antiviral and anti-car

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Lichen Secondary Metabolites Bioactive Properties and Pharmaceutical Potential Second Edition

Lichen Secondary Metabolites

Branislav Ranković Editor

Lichen Secondary Metabolites Bioactive Properties and Pharmaceutical Potential Second Edition

Editor Branislav Ranković Faculty of Science University of Kragujevac Kragujevac, Serbia

ISBN 978-3-030-16813-1 ISBN 978-3-030-16814-8 https://doi.org/10.1007/978-3-030-16814-8

(eBook)

# Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG. The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

1

Lichens as a Potential Source of Bioactive Secondary Metabolites . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Branislav Ranković and Marijana Kosanić

1

2

Lichens Used in Traditional Medicine . . . . . . . . . . . . . . . . . . . . . . . . Stuart D. Crawford

31

3

Lichen Secondary Metabolites as Potential Antibiotic Agents . . . . . . Marijana Kosanić and Branislav Ranković

99

4

Studies on Antioxidant Properties of Lichen Secondary Metabolites . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 Marijana Kosanić and Branislav Ranković

5

Investigations of Lichen Secondary Metabolites with Potential Anticancer Activity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155 Tatjana Stanojković

6

Antigenotoxic Effect of Some Lichen Metabolites . . . . . . . . . . . . . . . 175 Hülya Sivas

7

Lichen Secondary Metabolites as Possible Antiviral Agents . . . . . . . 199 Damian C. Odimegwu, Kenneth Ngwoke, Chika Ejikeugwu, and Charles O. Esimone

8

Antineurodegenerative and Antidiabetic Activity of Lichens . . . . . . . 215 Marijana Kosanić and Branislav Rankov