Life Extension Lessons from Drosophila
This book looks at aging through research on Drosophila, the fruit fly that is one of the most widely used model organisms in biogerontology. Work in model organisms can expand the theoretical knowledge of aging: it yields valuable insight into the molecu
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Alexander M. Vaiserman Alexey A. Moskalev Elena G. Pasyukova Editors
Life Extension Lessons from Drosophila
Healthy Ageing and Longevity Volume 3
Series editor Suresh I.S. Rattan, Aarhus, Denmark
More information about this series at http://www.springer.com/series/13277
Alexander M. Vaiserman · Alexey A. Moskalev Elena G. Pasyukova Editors
Life Extension Lessons from Drosophila
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Editors Alexander M. Vaiserman Laboratory of Epigenetics Institute of Gerontology Kiev Ukraine
Elena G. Pasyukova Laboratory of Genome Variation Institute of Molecular Genetics of RAS Moscow Russia
Alexey A. Moskalev Laboratory of Molecular Radiobiology and Gerontology Institute of Biology of Komi Science Center of Ural Branch of RAS Syktyvkar, Komi Republic Russia
ISSN 2199-9007 ISSN 2199-9015 (electronic) Healthy Ageing and Longevity ISBN 978-3-319-18325-1 ISBN 978-3-319-18326-8 (eBook) DOI 10.1007/978-3-319-18326-8 Library of Congress Control Number: 2015938726 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Preface
Human life expectancy has nearly doubled over the last 100 years due, in part, to a wide range of novel medical technologies and treatments. The trend toward increased life expectancy in the developed countries is accompanied by the increased number of people surviving to an advanced age and having different chronic age-associated pathologies. This trend leads to the need to understand the genetic and physiological mechanisms underlying aging processes and particularly those that promote healthy aging. Moreover, in recent years, substantial evidence has emerged supporting the possibility of the radical human life extension, primarily due to the rapid development of genetic and stem cell-based technologies. In the development
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