Lifestyle and Psychosocial Risk Factors Predict Non-adherence to Medication
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Lifestyle and Psychosocial Risk Factors Predict Non-adherence to Medication Brooke Aggarwal, Ed.D., M.S. & Lori Mosca, M.D., M.P.H., Ph.D.
Published online: 29 July 2010 # The Society of Behavioral Medicine 2010
Abstract Blood pressure and cholesterol reduction have proven effective to reduce cardiovascular disease (CVD) risk, yet adherence to medical therapy is suboptimal and contributing factors to non-adherence are not well-established. The purpose of this study was to determine the prevalence and predictors of non-adherence to blood pressure and cholesterollowering medications in individuals who participated in an NHLBI-sponsored evaluation of a hospital-based screening and outreach program for high-risk employees and the community. This was a cross-sectional study of 371 adults (mean age 60 years, 57% female, 60% non-white) who were eligible to participate if they were men >40 years, women >50 years, or had established CVD or CVD-risk equivalent. Each participant received a comprehensive standardized CVD screening evaluation; medication non-adherence was defined as missing any pills for high blood pressure or abnormal cholesterol in the past week. Associations between participant demographics, lifestyle and psychosocial risk factors, and non-adherence were assessed using logistic regression to adjust for confounders. The prevalence of taking medication for high blood pressure or abnormal cholesterol in the study population was 48% and 38%, respectively. Among those participants, 14% reported missing high blood pressure pills and 23% reported B. Aggarwal : L. Mosca Columbia University Medical Center, 601 West 168th Street, Suite 43, New York, NY 10032, USA B. Aggarwal : L. Mosca (*) Preventive Cardiology Program, NewYork Presbyterian Hospital, 601 West 168th Street, Suite 43, New York, NY 10032, USA e-mail: [email protected] e-mail: [email protected]
missing cholesterol pills in the past week. Significant (p
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