Locally advanced leiomyosarcoma of the spleen. A case report and review of the literature
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Case report
Locally advanced leiomyosarcoma of the spleen. A case report and review of the literature Paolo Piovanello*1, Vincenzo Viola1, Giampaolo Costa1, Massimiliano Carletti1, Andrea Cecera1, Fabrizio Turchetta1, Roberto Iudicone1, Giuseppe Catalano1, Antonello Santucci1, Franco Recchia2, Loredana Fiorillo3, Maria Antonella Menichella3 and Giovanni Baiano1 Address: 1Department of General and Thoracic Surgery, "San Giovanni di Dio" Hospital – Fondi (Latina), Italy, 2Department of Anesthesiology – "San Giovanni di Dio" Hospital – Fondi (Latina), Italy and 3Operative Room Nursery, "San Giovanni di Dio" Hospital – Fondi (Latina), Italy Email: Paolo Piovanello* - [email protected]; Vincenzo Viola - [email protected]; Giampaolo Costa - [email protected]; Massimiliano Carletti - [email protected]; Andrea Cecera - [email protected]; Fabrizio Turchetta - [email protected]; Roberto Iudicone - [email protected]; Giuseppe Catalano - [email protected]; Antonello Santucci - [email protected]; Franco Recchia - [email protected]; Loredana Fiorillo - [email protected]; Maria Antonella Menichella - [email protected]; Giovanni Baiano - [email protected] * Corresponding author
Published: 28 November 2007 World Journal of Surgical Oncology 2007, 5:135
doi:10.1186/1477-7819-5-135
Received: 25 May 2007 Accepted: 28 November 2007
This article is available from: http://www.wjso.com/content/5/1/135 © 2007 Piovanello et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Leiomyosarcomas are rare tumours, predominantly localized in the stomach, small intestine and retroperitoneum. Only one case of primary leiomyosarcoma of the spleen is described in human beings in literature. Case presentation: We report a case of locally advanced primary leiomyosarcoma of the spleen in a 54 year-old woman, diagnosed only after splenectomy, performed with the suspicion of splenic haematoma. Conclusion: Due to the lack of cases, no specific chemotherapy regimen has been tested to provide a longer survival.
Background Leiomyosarcomas are rare tumours, predominantly localized in the stomach, small intestine and retroperitoneum. Only one case of primary leiomyosarcoma of the spleen is described in human beings in literature.
Case presentation A 54-year-old Caucasian woman was referred to our department with a history of left-sided abdominal pain,
lasting about 8 months. No other signs or symptoms were present at the moment of observation. Past medical history revealed no significant medical problems. Hysterectomy for endometriosis had been performed ten years before admission. No history of carcinogenic exposure was reported. At admission physical examination revealed a palpable spleen 4 cm below the left costal margin. No hepatomegaly was noted. Laboratory exams sh
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