Long-Term Prognostic Role of Computed Tomography Coronary Angiography for Stable Angina
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(2020) 22:22
Imaging (Q Truong, Section Editor)
Long-Term Prognostic Role of Computed Tomography Coronary Angiography for Stable Angina Mohammed N. Meah, MBChB1 Michelle C. Williams, MBChB, PhD1,2,* Address 1 BHF Centre for Cardiovascular Science, University of Edinburgh, Chancellor’s Building, SU305, 49 Little France Crescent, Edinburgh, EH16SUF, UK *,2 Edinburgh Imaging facility QMRI, University of Edinburgh, Edinburgh, UK Email: [email protected]
* The Author(s) 2020
This article is part of the Topical Collection on Imaging Keywords Computed tomography coronary angiography I Coronary artery disease I Stable angina I Cardiac imaging
Abstract Purpose of review Chest pain is a common presentation, and there are a wide variety of ways in which it can be investigated and treated. There is growing interest in whether the way we reach a diagnosis of angina can affect the long-term prognosis. In addition to its unparalleled negative predictive value, computed tomography coronary angiography (CCTA) gives anatomical information on the extent and severity of coronary artery disease. This article discusses recent research into the ability of CCTA to predict and improve long-term prognosis for patients with stable angina. Recent findings Results from retrospective studies, randomised controlled trials and metaanalyses all suggest that initial investigation with computed tomography coronary angiography confers a prognostic benefit. In addition, the most recent studies have shown that the assessment of plaque burden and plaque constituents is predictive of long-term outcomes. Summary Management of stable chest pain should be guided by a CCTA-based approach. Future research should focus on whether incorporating plaque analysis strategies into clinical practice confers additional benefit.
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Curr Treat Options Cardio Med
(2020) 22:22
Introduction To improve upon prognosis, one must make an accurate diagnosis. The term prognosis was coined by Hippocrates, to mean “foreseeing and foretelling” [1]. When doctors give a prognostic statement, they predict the future course of an individual’s condition. However, in order to precisely predict the prognosis in any individual, it is vital that an accurate diagnosis is made. A diagnosis traditionally identifies a person as having or not having a disease. Accurate diagnosis and acknowledgement that there is a prognostic spectrum dependent on the severity
of disease are important and can focus treatments on those who stand to gain the most benefit [2]. There is growing interest in how improved diagnosis can positively impact upon prognosis. In those with chest pain for example, accurate diagnosis of the presence and severity of coronary artery disease has the potential to alter management and improve outcomes. This article will discuss the role of computed tomography coronary angiography (CCTA) in assessing and improving the long-term prognosis of patients with stable angina.
Improving prognosis for patients with stable angina To understand how CCTA can aff
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