Lutetium-177-PSMA-therapy/225-actinium-PSMA
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Thrombocytopenia, anaemia and leucopenia: case report In a study of 43 male patients, a male patient [age not stated] was described, who developed grade 3 thrombocytopenia, grade 2 anaemia and leucopenia during combination treatment with lutetium-177-PSMA-therapy and 225-actinium-PSMA for refractory metastatic castration resistant prostate cancer [routes, dosages, duration of treatment to reactions onset and outcomes not stated]. Author comment: "G3 thrombocytopenia, G2 anemia and leucocytopenia were noted in 1 patient with progressive disease. Otherwise, there was no hematological toxicity". Kulkarni HR, et al. Tandem PSMA radioligand therapy using Ac-225 and Lu-177 in advanced prostate cancer: Safety and efficacy. European Journal of Nuclear Medicine and Molecular Imaging 46 (Suppl. 1): S236-S237 (plus oral presentation) abstr. OP-619, No. 1, Oct 2019. Available from: URL: http://doi.org/10.1007/ 803433928 s00259-019-04486-2 [abstract] - Germany
0114-9954/19/1779-0001/$14.95 Adis © 2019 Springer Nature Switzerland AG. All rights reserved
Reactions 16 Nov 2019 No. 1779
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