Magnetic Particle Imaging An Introduction to Imaging Principles and
This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perfo
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Tobias Knopp • Thorsten M. Buzug
Magnetic Particle Imaging An Introduction to Imaging Principles and Scanner Instrumentation With the Collaboration of ¨ Borgert and Bernhard Gleich Jorn
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Dr. Tobias Knopp Institut f¨ur Medizintechnik Universit¨at zu L¨ubeck L¨ubeck Germany
Prof. Dr. Thorsten M. Buzug Institut f¨ur Medizintechnik Universit¨at zu L¨ubeck L¨ubeck Germany
ISBN 978-3-642-04198-3 ISBN 978-3-642-04199-0 (eBook) DOI 10.1007/978-3-642-04199-0 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2012937726 © Springer-Verlag Berlin Heidelberg 2012 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
This volume gives an introduction into the novel imaging technique magnetic particle imaging (MPI), which was invented by Bernhard Gleich in 2001 at Philips Research, Hamburg. MPI allows to determine the spatial distribution of magnetic nanoparticles, which can be used as tracers for medical imaging. The method provides a unique combination of features, which makes it a promising method for several clinical applications. It provides high spatial and temporal resolution, high sensitivity and is inherently quantitative. In contrast to several clinically used imaging methods, MPI is free of ionizing radiation and is thus con
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