Management of Advanced Prostate Cancer
This textbook summarizes the state of the art in the management of locally advanced and metastatic prostate cancer with the aim of providing the knowledge required for optimal treatment decision making in individual cases. Readers will find comprehensive
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Management of Advanced Prostate Cancer
Choung Soo Kim Editor
Management of Advanced Prostate Cancer
Editor Choung Soo Kim Department of Urology Asan Medical Center Seoul Soul-t´ukpyolsi South Korea
ISBN 978-981-10-6942-0 ISBN 978-981-10-6943-7 (eBook) https://doi.org/10.1007/978-981-10-6943-7 Library of Congress Control Number: 2018949600 © Springer Nature Singapore Pte Ltd. 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by Springer Nature, under the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Preface
Prostate cancer is the second most common cancer in men worldwide and the fifth cause of cancer-related death in men. As the economy developed, the incidence of prostate cancer increased and substantial public health burden was on the rise. Although the examination of prostate-specific antigen increased, the chance of early detection of prostate cancer and advanced prostate cancer still exists and most cancer-related deaths are caused by not-localized, but advanced prostate cancer. Until now there is no perfect solution to overcome the advanced prostate cancer. Many efforts have been made and are under way to control the disease in various fields. There are many clinical trials to treat metastatic prostate cancer whether it is hormone sensitive or castration resistant. New treatment approaches were approved after successful clinical trials. Therefore, our mission was to show the journey to overcome the advanced prostate cancer. The contents of the book range from localized high-risk prostate cancer to metastatic castration-resistant prostate cancer. We divided the book into four parts of treatment: surgery, radiotherapy, androgen deprivation therapy, and systemic chemotherapy-immunotherapy. In
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