Matrix Metalloproteinases in Tissue Remodelling and Inflammation
Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. MMP synthesis and functions are regulated by three major mechanisms including transcr
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Progress in Inflammation Research
Series Editor Prof. Michael J. Parnham PhD Director of Preclinical Discovery Centre of Excellence in Macrolide Drug Discovery GlaxoSmithKline Research Centre Zagreb Ltd. Prilaz baruna Filipovic´a 29 HR-10000 Zagreb Croatia Advisory Board G. Z. Feuerstein (Wyeth Research, Collegeville, PA, USA) M. Pairet (Boehringer Ingelheim Pharma KG, Biberach a. d. Riss, Germany) W. van Eden (Universiteit Utrecht, Utrecht, The Netherlands)
Forthcoming titles: Microarrays in Inflammation, A. Bosio, B. Gerstmayer (Editors), 2008 New Therapeutic Targets in Rheumatoid Arthritis, P.-P. Tak (Editor), 2009 Inflammatory Cardiomyopathy (DCM) – Pathogenesis and Therapy, H.-P. Schultheiß, M. Noutsias (Editors), 2009 Th 17 Cells: Role in Inflammation and Autoimmune Disease, B. Ryffel, F. Di Padova (Editors), 2009 Occupational Asthma, T. Sigsgaard, D. Heederick (Editors), 2009 Nuclear Receptors and Inflammation, G.Z. Feuerstein, L.P. Freedman, C.K. Glass (Editors), 2009 (Already published titles see last page.)
Matrix Metalloproteinases in Tissue Remodelling and Inflammation
Vincent Lagente Elisabeth Boichot Editors
Birkhäuser Basel · Boston · Berlin
Editors Vincent Lagente Elisabeth Boichot INSERM U620 Faculté des Sciences Pharmaceutiques et Biologique Université de Rennes 1 Avenue du Professeur Léon Bernard 2 35043 Rennes CX France
Library of Congress Control Number: 2008932707
Bibliographic information published by Die Deutsche Bibliothek Die Deutsche Bibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data is available in the internet at http://dnb.ddb.de
ISBN 978-3-7643-8584-2 Birkhäuser Verlag AG, Basel – Boston – Berlin The publisher and editor can give no guarantee for the information on drug dosage and administration contained in this publication. The respective user must check its accuracy by consulting other sources of reference in each individual case. The use of registered names, trademarks etc. in this publication, even if not identified as such, does not imply that they are exempt from the relevant protective laws and regulations or free for general use. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. For any kind of use, permission of the copyright owner must be obtained. © 2008 Birkhäuser Verlag AG Basel · Boston · Berlin P.O. Box 133, CH-4010 Basel, Switzerland Part of Springer Science+Business Media Printed on acid-free paper produced from chlorine-free pulp. TCF ' Cover design: Markus Etterich, Basel Cover illustration: see page 47. With friendly permission of Annie Pardo. Printed in Germany ISBN 978-3-7643-8584-2 987654321
e-ISBN 978-3-7643-8585-9 www.birkhauser.ch
Contents
List of contributors Preface
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