Mesotherapy in Aesthetic Medicine
Mesotherapy is a minimally invasive technique which involves microinjections of mixture of compounds into the mesoderm or middle layer of the skin to treat local medical and a variety of cosmetic conditions. Although mesotherapy has been available for ove
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Maya Vedamurthy
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Introduction
Mesotherapy is a technique of delivering small quantities of vitamins, minerals, amino acids, conventional medications, and preparations directly into the mesoderm to promote a biological response and reverse pathology in the treated area [1, 2]. Mesotherapy was invented by Michel Pistor in 1952 to treat conditions in rheumatology, sports traumatology, infectious diseases, vascular diseases and mainly as a pain-relieving technique [3]. Pistor described mesotherapy as “smallest dose, infrequently in the correct location”. The proposed mechanism of action of mesotherapy is that solutions injected intracutaneously remain in the area longer than they would by deeper injection as these solutions continually penetrate into the deeper tissues. Mesotherapy therefore appears to be a unique technique to administer medicines local to the pathology while the skin serves as a natural time – release system. Traditional Mesotherapy has now evolved into a new era of aesthetic medicine where it is employed in cosmetic applications such as removal of fat and cellulite, and body contouring. The North American experience began when Bissoon learned the technique in France and later popularized it in America.
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Mesotherapy is used in the treatment of: 1. Cellulite 2. Weight loss and body sculpting 3. Local fat deposits – xanthelasma, lipoma 4. Alopecia 5. Facial rejuvenation – wrinkles, skin tightening 6. Hyperpigmentation Other dermatologic conditions purported to benefit using mesotherapy [1]: 1. Acne 2. Melasma 3. Eczema 4. Hypertrophic or keloid scars 5. Leg ulceration 6. Photoaging 7. Pruritus 8. Psoriasis 9. Striae distensae 10. Telangiectasias 11. Venous stasis 12. Vitiligo
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M. Vedamurthy Consultant Dermatologist, Department of Dermatology, Apollo Hospitals, Chennai, TN, India e-mail: [email protected]
Common Applications of Mesotherapy
Candidate Selection
Adults between the ages of 18 and 75 years in good physical and medical health and with realistic expectations are candidates for mesotherapy. A detailed medical history and physical examination is mandatory to administering mesotherapy.
M.A. Shiffman and A. Di Giuseppe (eds.), Cosmetic Surgery, DOI 10.1007/978-3-642-21837-8_13, © Springer-Verlag Berlin Heidelberg 2013
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M. Vedamurthy
Contraindications to Mesotherapy
1. 2. 3. 4. 5. 6.
Pregnancy and lactation Insulin-dependent diabetes History of strokes History of cancer History of thromboembolic phenomena Patients on medications like aspirin, warfarin, heparin, etc. 7. Severe heart disease 8. Active kidney or hepatic diseases 9. Allergy to one of the components
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Products Commonly Used in Mesotherapy
The products selected for mesotherapy are based on the pharmacology. There is a wide range of products for various indications. Sometimes a combination of these products is used to achieve desired results. When the ingredients are reconstituted, they must be used within 24 h or discarded [4].
13.5.1 Fat/Cellulite 1. Phosphatidylcholine (a) Pol
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