Metaanalysis of Trials of Tirilazad Mesylate in Aneurysmal SAH
Tirilazad mesylate is the first of the new generation of 21-aminosteroid drugs [1 ] to come into clinical use. The steroid molecule was modified to remove the usual steroid side effects, and by the addition of a large amine molecule to the 21 carbon. It i
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Cerebral Vasospasm Edited by R. W. Seiler and H.-J. Steiger Acta Neurochirurgica Supplement 77
Prof. Dr. R. W. Seiler Neurochirurgische Univ.-Klinik, Inselspital, Bern, Switzerland
Univ.-Prof. Dr. H.-J. Steiger Neurochirurgische Univ.-Klinik, Klinikurn GroBhadern, Miinchen, Germany
This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machines or similar means, and storage in data banks.
© 2001 Springer-Verlag/Wien Product Liability: The publisher can give no guarantee for all the information contained in this book. This does also refer to information about drug dosage and application thereof. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Typesetting: Asco Typesetters, Hong Kong
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With 90 partly coloured Figures Library of Congress Cataloging-in-Publication Data Cerebral vasospasm / edited by R. W. Seiler and H.-J. Steiger. p.; cm. - (Acta neurochirurgica. Supplement; 77) Includes bibliographical references and index. ISBN 3211836500 (alk. paper) I. Cerebrovascular spasm-Congresses. I. Seiler, RolfW. II. Steiger, Hans-Jakob, 1953- III. International Conference on Cerebral Vasospasm (7th: 2000 Interlaken, Switzerland) IV. Series. [DNLM: 1. Vasospasm, Intracranial-Congresses. WL 355 C41306 2001] RC388.5 .C39782 2001 616.8'I-dc21 2001020800
ISSN 0065-1419 ISBN 3-211-83650-0 Springer-Verlag Wien New York
Preface
This book contains the proceedings of the 7th International Conference on Cerebral Vasospasm, held in Interlaken, Switzerland, June 2000. Previous meetings devoted to cerebral vasospasm were held in Jackson, Mississippi (1972), Amsterdam, Netherlands (1979), Charlottesville, Virginia (1987), Tokyo (1990), Edmonton, Canada (1993) and Sydney, Australia (1997). The book gives the state of the art in reviews of the major aspects of cerebral vasospasm by invited authors, and selected articles of the conference presenting important results of the most recent research in basic sciences and clinical management of cerebral vasospasm. Prof. Helge Nornes from Oslo, Norway, was the honored guest of the conference. Prof. Nornes has made major contributions to the evaluation and clinical management of cerebral vasospasm. A tribute to
his life and his clinical and scientific work was published recently in Supplement 72 of Acta Neurochirurgica (1999). The editors gratefully acknowledge the help of the staff of the Department of Neurosurgery of the University Hospital Berne, and especially of Mrs. Nicole Reinert-Fliickiger, in the organization and running of the 7th Interna
