Models of Photosynthetic Electron Transport
- PDF / 2,071,982 Bytes
- 15 Pages / 612 x 792 pts (letter) Page_size
- 47 Downloads / 253 Views
BIOPHYSICS
Models of Photosynthetic Electron Transport G. Yu. Riznichenkoa, *, N. E. Belyaevaa, A. N. Diakonovaa, I. B. Kovalenkoa, A. S. Maslakova, T. K. Antala, S. N. Goryacheva, T. Yu. Plyusninaa, V. A. Fedorova, S. S. Khruscheva, and A. B. Rubina aDepartment
of Biology, Moscow State University, Moscow, 119991 Russia *e-mail: [email protected]
Received February 5, 2020; revised February 5, 2020; accepted June 15, 2020
Abstract—Energy transduction reactions in the photosynthetic membrane are a primary step in storing solar energy to be used later in biosynthetic and other processes in living systems. This review summarizes the recent data on modeling photosynthetic electron transport that were obtained at the Department of Biology, Moscow State University. Mathematical models of various types were used to simulate the processes that occur at the levels of macromolecules, their complexes, and molecular ensembles and at the subcellular and cell levels. Detailed kinetic models act by fitting model curves to experimental data and make it possible to estimate the contributions of individual processes to the observed processes and to identify the system parameters. The Monte Carlo method helps to simulate the processes that occur in ensembles of several millions of photosynthetic chains. Brownian and molecular dynamics were used to study the formation of electrontransport protein–protein complexes. A combination of the above methods provides the ability to study the basic mechanisms of energy conversion in multiscale energy-converting systems, such as the system of primary photosynthetic processes. Keywords: photosynthesis, electron transport, kinetic models, Brownian dynamics, molecular dynamics, Monte Carlo method DOI: 10.1134/S0006350920050152
INTRODUCTION Mathematical and computer models make it possible to integrate the data on individual components of a system, to evaluate the parameters from experimental data, and to study the mechanisms involved in regulating the processes of matter and energy transformation in photosynthesis. Because the kinetics of redox transformations in response to short light flashes can directly be recorded for individual components of the system, model parameters can be correctly identified using data from kinetic experiments. This provides a substantial advantage to photosynthetic system models compared with models of metabolic networks, where changes in the concentrations of individual internal metabolites of a system are not feasible to monitor in real time. The processes of light absorption, primary charge separation, and charge stabilization occur in multienzyme complexes that are incorporated in the membrane and belong to photosynthetic reaction centers (RCs) of photosystems I and II (PS I and PS II) [1– 4]. Experiments with various types of photosynthetic RCs showed that constant structural and functional organization is preserved in these systems optimized Abbreviations: PS I—photosystem I; PS II—photosystem II; RC—reaction center; PQ—plastoquinone; Pc—plastocyanin; Fd—
Data Loading...
