Modern Concepts in Gastroenterology Volume 2
Once again the gastroenterologists of northwestern Canada have come out with a series of essays advancing important modem concepts. As indefatigable as ever, they bring together the latest in clinical-pathophysiological considera tions for the clinician.
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TOPICS IN GASTROENTEROLOGY Series Editor: Howard M. Spiro, M.D. Yale University School of Medicine
COLON Structure and Function Edited by Luis Bustos-Fernandez, M.D. KEY FACTS IN GASTROENTEROLOGY Jonathan Halevy, M.D. MEDICAL ASPECTS OF DIETARY FIBER Edited by Gene A. Spiller, Ph.D., and Ruth McPherson Kay, Ph.D. MODERN CONCEPTS IN GASTROENTEROLOGY, Volume 1 Edited by Alan B. R. Thomson, M.D., Ph.D., L. R. DaCosta, M.D., and William C. Watson, M.D. MODERN CONCEPTS IN GASTROENTEROLOGY, Volume 2 Edited by Eldon Shaffer, M.D., and Alan B. R. Thomson, M.D., Ph.D. NUTRITION AND DIET THERAPY IN GASTROINTESTINAL DISEASE Martin H. Floch, M.S., M.D., F.A.C.P. PANCREATITIS Peter A. Banks, M.D.
A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.
Modern Concepts in Gastroenterology Volume 2 Edited by
Eldon Shaffer, M. D. University of Calgary Calgary, Alberta, Canada
and
Alan B. R. Thomson, M. D., Ph. D.
The University of Alberta Edmonton, Alberta, Canada
PLENUM MEDICAL BOOK COMPANY NEW YORK AND LON DON
The Library of Congress cataloged the first volume of this title as follows: Modern concepts in gastroenterology. (Topics in gastroenterology) Includes bibliographies and index. 1. Gastrointestinal system-Diseases. I. Thomson, A. B. R. (Alan Bryan Robert), 1943. II. DaCosta, L. R. III. Watson, William C. IV. Series. 616.3'3 87-102291 RC801.M58 1986
ISBN-13: 978-1-4612-8079-8 DOl: 10.1007/978-1-4613-0781-5
e-ISBN-13: 978-1-4613-0781-5
© 1989 Plenum Publishing Corporation Softcover reprint ofthe hardcover 1st edition 1989 233 Spring Street, New York, N.Y. 10013 Plenum Medical Book Company is an imprint of Plenum Publishing Corporation All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
This work is dedicated to Beryl, Andrea, Emily, and Ali and to Jeannette, James, Matthew, Jessica, and Benjamin
Cantri butars
L. M. Blendis, Department of Medicine, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada M5G 2C4 Jared M. Diamond, Department of Physiology, University of California-Los
Angeles School of Medicine, Los Angeles, California 90024 Martin F. Kagnoff, Laboratory of Mucosal Immunology, Department of Medi-
cine, University of California-San Diego, La Jolla, California 92093 Young S. Kim, Gastrointestinal Research Laboratory, Veterans Administration
Medical Center, and Department of Medicine, University of CaliforniaSan Francisco, San Francisco, California 94121 B. Langer, Department of Surgery, University of Toronto, Toronto, Ontario,
Canada MG5 lL5 Michael D. Levitt, Research Service, Veterans Administration Medical Center,
and Department of Medicine, University of Minnesota, Minneapolis, Mi
