Modern research of TCM etiology and pathogenesis theory and translational medicine
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MEETING ABSTRACT
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Modern research of TCM etiology and pathogenesis theory and translational medicine Ping Liu From 2012 Sino-American Symposium on Clinical and Translational Medicine (SAS-CTM) Shanghai, China. 27-29 June 2012
To develop the basic theory based on clinical practice, and further to guide clinical for improving the therapeutic effect is one of the important characteristics of TCM thinking way. In a sense, the development and innovation of TCM basic theory is equivalently a process of translational medicine. The typical examples are “defense, qi, nutrient and blood pattern identification” and “triple energizer pattern identification”. The knowledge and technology using in modern integration of TCM syndrome and western medicine disease are always as a starting point to solve the clinical problems, to improve the therapeutic efficacy of the disease and the patient’s quality of life. The methods of TCM are to establish a series of systematic research from the clinical (efficacy) – experiment – drug efficacy mechanism, and constantly to find and solve new problems, thereby to promote the development of medicine. TCM etiology and pathogenesis theory is based on the visceral manifestation, meridian and collateral, essence, Qi, blood, fluid and humor, etc. Judging by clinical observation, it is eventually verified whether the treatment effect can be overall restored. Against pathological features of modern diseases, TCM has given full play to the advantage of macro overall thinking, cognized and found TCM basic etiology and pathogenesis of the disease or the critical key affecting disease development and prognosis. To explore TCM effective therapies and formulas, further to develop TCM etiology and pathogenesis theory for understanding deeply western diseases, is essentially a kinds of the crossover and recreation process between TCM and western medicine. The etiology and pathogenesis theory belongs to the “principles” scope within TCM “principles, methods, formulas and medicinals”. It must be verificated repeatly Correspondence: [email protected] Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China
which combines closely with the therapeutic effects. Then it could form the etiology and pathogenesis theory which guides widely the diagnosis and treatment of clinical disease. That also is a key issue of TCM possessing “translational medicine” features. In order to adapt to the development of modern society, and promote the theory innovation, TCM etiology and pathogenesis theory must adhere to the own theory and thinking principles, connect closely with the development of modern science, explore more convincing scientific evidence, and be constantly revised and improved in practice. Thereby it will fully show the practical significance in improving the clinical efficacy. At the same time, it is also an important way that finds a new prescription or a new use of mature prescription on treatment modern complex, refractory disease. We have once analyzed the patients with po
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