Mucin-hypersecreting bile duct neoplasm characterized by clinicopathological resemblance to intraductal papillary mucino
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Case report
Mucin-hypersecreting bile duct neoplasm characterized by clinicopathological resemblance to intraductal papillary mucinous neoplasm (IPMN) of the pancreas Yo-ichi Yamashita*1,2, Kengo Fukuzawa2, Akinobu Taketomi1, Shinichi Aishima3, Tomoharu Yoshizumi1, Hideaki Uchiyama1, Eiji Tsujita1, Norifumi Harimoto1, Noboru Harada1, Kenzo Wakasugi2 and Yoshihiko Maehara1 Address: 1Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 8128582, Japan, 2Department of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyo-machi, Oita 870-0033, Japan and 3Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan Email: Yo-ichi Yamashita* - [email protected]; Kengo Fukuzawa - [email protected]; Akinobu Taketomi - [email protected]; Shinichi Aishima - [email protected]; Tomoharu Yoshizumi - [email protected]; Hideaki Uchiyama - [email protected]; Eiji Tsujita - [email protected]; Norifumi Harimoto - [email protected]; Noboru Harada - [email protected]; Kenzo Wakasugi - [email protected]; Yoshihiko Maehara - [email protected] * Corresponding author
Published: 28 August 2007 World Journal of Surgical Oncology 2007, 5:98
doi:10.1186/1477-7819-5-98
Received: 5 May 2007 Accepted: 28 August 2007
This article is available from: http://www.wjso.com/content/5/1/98 © 2007 Yamashita et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Although intraductal papillary mucinous neoplasm (IPMN) of the pancreas is acceptable as a distinct disease entity, the concept of mucin-secreting biliary tumors has not been fully established. Case presentation: We describe herein a case of mucin secreting biliary neoplasm. Imaging revealed a cystic lesion 2 cm in diameter at the left lateral segment of the liver. Duodenal endoscopy revealed mucin secretion through an enlarged papilla of Vater. On the cholangiogram, the cystic lesion communicated with bile duct, and large filling defects caused by mucin were observed in the dilated common bile duct. This lesion was diagnosed as a mucin-secreting bile duct tumor. Left and caudate lobectomy of the liver with extrahepatic bile duct resection and reconstruction was performed according to the possibility of the tumor's malignant behavior. Histological examination of the specimen revealed biliary cystic wall was covered by micropapillary neoplastic epithelium with mucin secretion lacking stromal invasion nor ovarian-like stroma. The patient has remained well with no evidence of recurrence for 38 months since her operation. Conclusion: It is only rec
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