Multislice CT

The fourth edition of this well-received book offers a comprehensive update on recent developments and trends in the clinical and scientific applications of multislice computed tomography. Following an initial section on the most significant current techn

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onstantin Nikolaou · Fabian Bamberg  Andrea Laghi · Geoffrey D. Rubin Editors

Multislice CT Fourth Edition

Medical Radiology Diagnostic Imaging Series Editors Hans-Ulrich Kauczor Paul M. Parizel Wilfred C. G. Peh

For further volumes: http://www.springer.com/series/4354

Konstantin Nikolaou • Fabian Bamberg Andrea Laghi • Geoffrey D. Rubin Editors

Multislice CT Fourth Edition

Editors Konstantin Nikolaou Department of Radiology University Hospitals Tübingen Tübingen, Baden-Württemberg Germany Andrea Laghi Department of Surgical and Medical Sciences and Translational Medicine “Sapienza” – University of Rome Rome Italy

Fabian Bamberg Department of Diagnostic and Interventional Radiology University of Freiburg Freiburg Germany Geoffrey D. Rubin Department of Radiology Duke University School of Medicine Durham, NC USA

ISSN 0942-5373           ISSN 2197-4187 (electronic) Medical Radiology ISBN 978-3-319-42585-6    ISBN 978-3-319-42586-3 (eBook) https://doi.org/10.1007/978-3-319-42586-3 Library of Congress Control Number: 2018966548 © Springer International Publishing AG, part of Springer Nature 2001, 2004, 2009, 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

In Memoriam

This book is dedicated to our friend, colleague, and brilliant radiologist, who left us much too early. Gary Glazer was a CT pioneer, contributing some of our earliest understandings to the value of CT in the assessment of neoplasia, particularly metastatic involvement of mediastinal lymph nodes. He is, however, best remembered and revered for his leadership in building groundbreaking research programs rooted in a culture of collegiality and teamwork that was ahead of its time, serving as a model for innovation in a wo