Mycobacterial Skin Infections

This well-illustrated book is a comprehensive guide to the cutaneous clinical presentations of mycobacterial infections. The Mycobacterium genus includes over 170 species, nontuberculous mycobacteria (NTM) having been added to the obligate human pathogens

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Mycobacterial Skin Infections

Domenico Bonamonte  •  Gianni Angelini Editors

Mycobacterial Skin Infections

Editors Domenico Bonamonte University of Bari “Aldo Moro” Department of Biomedical Science and Human Oncology Bari Italy

Gianni Angelini University of Bari “Aldo Moro” Dermatology Bari Italy

English editing by Mary VC. Pragnell, B.A. (HONS).

ISBN 978-3-319-48537-9    ISBN 978-3-319-48538-6 (eBook) DOI 10.1007/978-3-319-48538-6 Library of Congress Control Number: 2017951315 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

To Davide Elizabeth Gianmarco

Preface

The overview of mycobacterial skin infections presented in this work is justified by the current worldwide increase in diseases induced by both old and new mycobacteria. Until the late 1980s, such diseases had been notably declining, but after that period, the trend reversed, and an exponential increase began to be observed. There are various reasons for this rise not only in developing countries but even in urban areas in the most developed nations. Being the cause of tuberculosis and leprosy, the Mycobacterium genus has probably caused mankind more suffering than all the other bacterial genera combined. Moreover, in addition to the obligate pathogens, namely, the Mycobacterium tuberculosis complex and M. leprae, this genus is continually being enriched by the addition of many other species. Although usually encountered as environmental saprophytes, in some conditions that depend on the host immune status, they can induce extremely severe, sometimes fatal, clinical pictures. It is well known that tuberculosis (TB) is one o