Nanomedicine: Risk, Safety, Regulation, and Public Health
Nanomedicine is a developing area of medicine, which uses the techniques and tools of nanotechnology to deliver the drugs using appropriate drug delivery systems. These are used for diagnosis, prevention, or treatment of acute or chronic diseases. At pres
- PDF / 283,757 Bytes
- 18 Pages / 439.37 x 666.142 pts Page_size
- 105 Downloads / 225 Views
21
Dewi Melani Hariyadi, Umi Athiyah, and Yashwant V. Pathak
Abstract
Nanomedicine is a developing area of medicine, which uses the techniques and tools of nanotechnology to deliver the drugs using appropriate drug delivery systems. These are used for diagnosis, prevention, or treatment of acute or chronic diseases. At present, there are three major areas where nanotechnology has been adopted in medicine, diagnostics, theranostics, drug delivery systems, and regenerative medicine. A new branch of toxicology has been proposed called nanotoxicology, and a lot of studies are reported about various risks involved with nanoapplications. This chapter covers various aspects of nanomedicines and risks involved in using nanomedicine, some of the safety concerns are discussed, and it also covers the regulatory aspect of nanoproducts under US FDA as well as approaches adopted by various countries. Finally, it discusses the public health and public opinion about nanoproducts and nanomedicines. Keywords
Nanomedicine · Nanotoxicity · Nanosafety · Public wellbeing · Regenerative medicine
D. M. Hariyadi · U. Athiyah Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia Y. V. Pathak (*) Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia College of Pharmacy, University of South Florida, Tampa, FL, USA e-mail: [email protected] # Springer Nature Singapore Pte Ltd. 2020 M. K. Das, Y. V Pathak (eds.), Nano Medicine and Nano Safety, https://doi.org/10.1007/978-981-15-6255-6_21
561
562
21.1
D. M. Hariyadi et al.
Introduction
21.1.1 NanoMedicine Nanomedicine is a developing area of medicine, which uses the techniques and tools of nanotechnology to deliver the drugs using appropriate delivery systems. These are recommended for diagnosis, prevention, or treatment of acute or chronic diseases. There are several devices and techniques that are used in surgery, which can also come under nanomedicine if they have the ability to prevent or treat the diseases [1]. The application of nanotechnology in developing new medicines is a part of the research and development worldwide. In USA and European Union (EU), it is recognized as an important enabling technology, capable of providing an innovative medical solution to address medical needs especially in the treatment of chronic diseases [2, 3]. Major applications of nanomedicine: Three major areas have been identified in the medical field for applications of nanotechnology in medicines: Diagnostics and Theranostics Nanomaterials have shown significant applications in the development of diagnostic tools for diagnosis, which provide information about the disease. These are also used to analyze or detect diseases or medical conditions, which can be useful in treating thee conditions. Nanodiagnostics is used to describe application of nanobiotechnology in diagnosis, which helps in developing personalized cancer therapy. It is supported by pharmacogenetics, pharmacogenomics, and pharmacoproteomic information. It also considers environmental factors that influence the response
Data Loading...
