Nanoscale Materials in Targeted Drug Delivery, Theragnosis and Tissue Regeneration
This book is the first of its kind to offer a comprehensive and up-to-date discussion of the use of nanoscale materials for biomedical applications, with a particular focus on drug delivery, theragnosis and tissue regeneration. It also describes in detail
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Nanoscale Materials in Targeted Drug Delivery, Theragnosis and Tissue Regeneration
Nanoscale Materials in Targeted Drug Delivery, Theragnosis and Tissue Regeneration
Sudesh Kumar Yadav Editor
Nanoscale Materials in Targeted Drug Delivery, Theragnosis and Tissue Regeneration
123
Editor Sudesh Kumar Yadav Department of Biotechnology Council of Scientific and Industrial Research-Institute of Himalayan Bioresource Technology Palampur, Himachal Pradesh India and Department of Biotechnology Center of Innovative and Applied Bioprocessing (CIAB) Mohali, Punjab India
ISBN 978-981-10-0817-7 DOI 10.1007/978-981-10-0818-4
ISBN 978-981-10-0818-4
(eBook)
Library of Congress Control Number: 2016936976 © Springer Science+Business Media Singapore 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Science+Business Media Singapore Pte Ltd.
Preface
Advancements in nanotechnology promise to revolutionize drug manufacturing, drug delivery, and medical diagnostics. Nanoscale materials hold great potential for medical applications due to their differential behavior at the cellular and molecular level. In this context, the term nanomedicine has been coined to refer to the application of nanoscale materials, which can be used as drug delivery vehicles to develop highly selective and effective drugs. Nanomedicine market is expected to grow at a compounded annual growth rate (CAGR) of 12.3 % during the period 2013–2019 to reach US$177.60 billion. The existing generation of drugs is largely based on small molecules with a mass of 1000 Da or less. These small molecules possess certain limitations, viz., poor bioavailability, lesser in vivo stability, first pass metabolism, non-targeted delivery to site of action, therapeutic ineffectiveness, side effects, etc. Nanomedicines have an upper hand compared to the standard drugs in view of several aspects, e.g., these reduce renal excre
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