Negative for Malignancy (NFM)
This chapter focuses on using an algorithmic approach to reporting negative findings in serous fluids, rather than providing detailed morphologic descriptions of benign entities. Specimens may be negative for malignancy (NFM) and yet be pathologic, but mo
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The International System for Serous Fluid Cytopathology
Ashish Chandra • Barbara Crothers Daniel Kurtycz • Fernando Schmitt Editors
The International System for Serous Fluid Cytopathology
Editors Ashish Chandra Cellular Pathology, Guy’s and St. Thomas’ NHS Foundation Trust London UK Daniel Kurtycz University of Wisconsin School of Medicine and Public Health, Department of Pathology and Laboratory Medicine and Wisconsin State Laboratory of Hygiene Madison, WI USA
Barbara Crothers Gynecology, Breast and Cytopathology Joint Pathology Center Silver Spring, MD USA Fernando Schmitt Department of Pathology Medical Faculty of Porto University and Unit of Molecular Pathology, Institute of Molecular Pathology and Immunology Porto University Porto Portugal
ISBN 978-3-030-53907-8 ISBN 978-3-030-53908-5 (eBook) https://doi.org/10.1007/978-3-030-53908-5 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To my great mentors – Professor Monisha Choudhury, Professor Dulcie Coleman and Dr Amanda Herbert – for their inspiration and encouragement through my early years in cytopathology. AC To my mother, for giving me freedom to explore, and to the cytopathology community for their cohesion, dedication and unflagging commitment to patients and their health through cytopathology. BC To my father, Frank Kurtycz, a family man and veteran, who educated three generations of descendants and provided us a model of honor and care. DK To all who helped, taught and supported me during my scientific career. FS
Foreword
Whilst the pendulum of cytopathology as a diagnostic modality in different organs and systems, through the years, swung both ways, its use in the di