Neurobiological Studies of Addiction in Chronic Pain States
Using rodent models, the contributors explore the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction. Combining various pain models with opioid self-administration and central administration pharmacotherapies all
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Carolyn A. Fairbanks Thomas J. Martin Editors
Neurobiological Studies of Addiction in Chronic Pain States
Contemporary Clinical Neuroscience
Carolyn A. Fairbanks • Thomas J. Martin Editors
Neurobiological Studies of Addiction in Chronic Pain States
Editors Carolyn A. Fairbanks Departments of Pharmaceutics, Pharmacology, Neuroscience University of Minnesota Minneapolis, MN, USA
Thomas J. Martin, Ph.D. Pain Mechanisms Laboratory Department of Anesthesiology Wake Forest University Health Sciences Winston-Salem, NC, USA
ISBN 978-1-4939-1855-3 ISBN 978-1-4939-1856-0 (eBook) DOI 10.1007/978-1-4939-1856-0 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2014953964 © Springer Science+Business Media New York 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
In 2011, the Institute of Medicine published a consensus report entitled “Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research”. This contribution documented and highlighted chronic pain as a public health problem. Those committed to improving prescription management strategies for chronic pain treatment, development of new approaches for pain management, and continuing the search for understanding the mechanisms underlyi
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