Neuroimaging Diagnosis for Alzheimer's Disease and Other Dementias

This book describes the latest modalities such as tau PET imaging for diagnosis of Alzheimer’s disease and other dementias, and also provides information on handling and analyzing imaging data that is not found in other books. In addition, it introduces r

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Hiroshi Matsuda Takashi Asada Aya Midori Tokumaru Editors

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Neuroimaging Diagnosis for Alzheimer's Disease and Other Dementias

Hiroshi Matsuda  •  Takashi Asada Aya Midori Tokumaru Editors

Neuroimaging Diagnosis for Alzheimer's Disease and Other Dementias

Editors Hiroshi Matsuda Integrative Brain Imaging Center National Center of Neurology & Psychiatry Kodaira Tokyo Japan Aya Midori Tokumaru Department of Diagnostic Radiology Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology Tokyo Japan

Takashi Asada Department of Psychiatry Institute of Clinical Medicine University of Tsukuba Tsukuba Ibaraki Japan

ISBN 978-4-431-55132-4    ISBN 978-4-431-55133-1 (eBook) DOI 10.1007/978-4-431-55133-1 Library of Congress Control Number: 2017951313 © Springer Japan 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Japan KK The registered company address is: Chiyoda First Bldg. East, 3-8-1 Nishi-Kanda, Chiyoda-ku, Tokyo 101-0065, Japan

Preface

Nowhere is the serious social problem of dementia more acute than in Japan, where an estimated one fourth of elderly persons already have or show signs of developing it. The prevalence of dementia has increased over the past few decades, either because of greater awareness and more accurate diagnosis, or because increased longevity has created a larger population of the elderly, the age group most commonly affected. More aging will develop from now on, and so it is predicted that 7 million elderly persons will be demented by 2025 in Japan. Although the diagnosis of dementia is still largely a clinical one, based on the history and disease course, neuroimaging has dramatically changed our ability to accurately diagnose it. The role of neuroimaging in dementia nowadays extends beyond its traditio