Neuroinflammation and Schizophrenia

This book provides a comprehensive summary of the cutting edge scientific evidence regarding the role of immune system in the pathogenesis and treatment of schizophrenia and related psychotic disorders. It illustrates the role of inflammation and immunity

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Golam M. Khandaker Urs Meyer Peter B. Jones Editors

Neuroinflammation and Schizophrenia

Current Topics in Behavioral Neurosciences Volume 44

Series Editors Mark A. Geyer, La Jolla, CA, USA Bart A. Ellenbroek, Wellington, New Zealand Charles A. Marsden, Nottingham, UK Thomas R.E. Barnes, London, UK Susan L. Andersen, Belmont, MA, USA

Current Topics in Behavioral Neurosciences provides critical and comprehensive discussions of the most significant areas of behavioral neuroscience research, written by leading international authorities. Each volume in the series represents the most informative and contemporary account of its subject available, making it an unrivalled reference source. Each volume will be made available in both print and electronic form. With the development of new methodologies for brain imaging, genetic and genomic analyses, molecular engineering of mutant animals, novel routes for drug delivery, and sophisticated cross-species behavioral assessments, it is now possible to study behavior relevant to psychiatric and neurological diseases and disorders on the physiological level. The Behavioral Neurosciences series focuses on translational medicine and cutting-edge technologies. Preclinical and clinical trials for the development of new diagnostics and therapeutics as well as prevention efforts are covered whenever possible. Special attention is also drawn on epigenetical aspects, especially in psychiatric disorders. CTBN series is indexed in PubMed and Scopus.

More information about this series at http://www.springer.com/series/7854

Golam M. Khandaker • Urs Meyer • Peter B. Jones Editors

Neuroinflammation and Schizophrenia

Editors Golam M. Khandaker Department of Psychiatry University of Cambridge School of Clinical Medicine Cambridge, UK

Urs Meyer Verhaltensneurobiologie ETH Zürich Schwerzenbach, Switzerland

Peter B. Jones Department of Psychiatry University of Cambridge School of Clinical Medicine Cambridge, UK

ISSN 1866-3370 ISSN 1866-3389 (electronic) Current Topics in Behavioral Neurosciences ISBN 978-3-030-39140-9 ISBN 978-3-030-39141-6 (eBook) https://doi.org/10.1007/978-3-030-39141-6 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and