New contraindication for calcium gluconate injection
- PDF / 122,628 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 2 Downloads / 153 Views
1
New contraindication for calcium gluconate injection Healthcare providers are being advised by the UK MHRA that calcium gluconate injection packed in smallvolume glass containers is now contraindicated for repeated or prolonged treatment in children or patients with renal impairment, due to the risk of aluminium exposure. Aluminium can be leached from glass following contact with calcium gluconate solution. Accumulation of aluminium may exert adverse effects on bone mineralisation and neurological development in children (aged < 18 years) and among those with renal impairment. To limit patient exposure to aluminium, particularly in vulnerable populations, calcium gluconate injection in small-volume glass containers is also contraindicated in the preparation of total parenteral nutrition solutions. The use of calcium gluconate injection packed in plastic containers is recommended, as the containers do not contain high levels of aluminium. Calcium gluconate injection in small-volume glass containers: new contraindications due to aluminium exposure risk. Drug Safety Update 4: A2, No. 801108743 1, Aug 2010
0114-9954/10/1314-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Reactions 14 Aug 2010 No. 1314
Data Loading...
