Niraparib
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Neutropenia and hypertension: 2 case reports In a study of 10 women, two adult women [exact ages not stated] were described, who developed grade 3 neutropenia (1 patient) and grade 3 hypertension (1 patient) during treatment with niraparib [routes and dosages not stated] for early expanded access ovarian cancer [time to reactions onsets not stated]. The niraparib was stopped due to neutropenia in one patient of these patients. The patient with grade 3 hypertension developed an acute kidney injury, requiring niraparib dose reduction [outcomes not stated]. Nieto Gomez P, et al. Niraparib maintenance therapy in early expanded access ovarian cancer patients. International Journal of Clinical Pharmacy 42: 285 abstr. PT031, No. 1, 803502838 Jan 2020. Available from: URL: http://doi.org/10.1007/s11096-019-00945-w [abstract]
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Reactions 26 Sep 2020 No. 1823
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