Non-coding RNAs and Inter-kingdom Communication

This book presents a state-of-the-art compilation of articles on the role of non-coding RNAs as pivotal molecules for establishing functional relationships between different organisms. It also describes how non-coding RNA molecules can act as dynamic comm

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ding RNAs and Inter-kingdom Communication

Non-coding RNAs and Inter-kingdom Communication

Ana Lúcia Leitão Francisco J. Enguita •

Editors

Non-coding RNAs and Inter-kingdom Communication

123

Editors Ana Lúcia Leitão Universidade Nova de Lisboa Caparica Portugal

ISBN 978-3-319-39494-7 DOI 10.1007/978-3-319-39496-1

Francisco J. Enguita Universidade de Lisboa Lisbon Portugal

ISBN 978-3-319-39496-1

(eBook)

Library of Congress Control Number: 2016941096 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland

Preface

More than 60 years ago, in 1954, James Watson and the Russian Physicist George Gamow founded the “RNA Tie club”, a scientific club of selected gentlemen members with the main objective of sharing their ideas and findings not yet mature enough to be published in scientific journals. Brainstorming sessions gave rise to many seminal concepts in cell biology, which were further demonstrated by laboratory experiences. Gamow postulated the concept of a “genetic code” based on the existence of triplets of bases (codons) that will translate the DNA language into protein amino acids. Furthermore, in the last 1950s, another illustrated member of the club, Francis Crick, enunciated the “adaptor theory” based on an intermediate molecule (transfer-RNA) that would be the physical link between nucleic acids and proteins. These ideas were later described in an essential Crick’s article, which is considered by many authors as the embryonic core of the concept of the RNA world. The RNA world stands on the idea that RNA molecules were the first precursors of the living cells, being the origin of the evolution of all biological macromolecules. Several arguments clearly support the theory that the primitive cells could be built over processing units based on RNA molecules, including t