Novel Strategies in the Design and Production of Vaccines

Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Co

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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan

Recent Volumes in this Series Volume 389 INTRACELLULAR PROTEIN CATABOLISM Edited by Koichi Suzuki and Judith S. Bond Volume 390 ANTIMICROBIAL RESISTANCE: A Crisis in Health Care Edited by Donald L. Jungkind, Joel E. Mortensen, Henry S. Fraimow, and Gary B. Calandra Volume 391 NATURAL TOXINS 2: Structure, Mechanism of Action, and Detection Edited by Bal Ram Singh and Anthony T. Tu Volume 392 FUMONISINS IN FOOD Edited by Lauren S. Jackson, Jonathan W. DeVries, and Lloyd B. Bullerman Volume 393 MODELING AND CONTROL OF VENTILATION Edited by Stephen J. G. Semple, Lewis Adams, and Brian J. Whipp Volume 394 ANTIVIRAL CHEMOTHERAPY 4: New Directions for Clinical Application and Research Edited by John Mills, Paul A. Volberding, and Laurence Corey Volume 395 OXYTOCIN: Cellular and Molecular Approaches in Medicine and Research Edited by Richard Ivell and John A. Russell Volume 396 RECENT ADVANCES IN CELLULAR AND MOLECULAR ASPECTS OF ANGIOTENSIN RECEPTORS Edited by Mohan K. Raizada, M. Ian Phillips, and Colin Sumners Volume 397 NOVEL STRATEGIES IN THE DESIGN AND PRODUCTION OF VACCINES Edited by Sara Cohen and Avigdor Shafferman

A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

NOVEL STRATEGIES IN THE DESIGN AND PRODUCTION OF VACCINES Edited by

Sara Cohen

and

Avigdor Shafferman

Israel Institute for Biological Research Ness-Ziona, Israel

Springer Science+Business Media, LLC

Library of Congress Cataloging-in-Publication Data On file

Proceedings of the 39th OHOLO Conference on Vaccines: Novel Strategies in Design and Production, held May 7-11,1995, in Eilat, Israel ISBN 978-1-4899-1384-5 ISBN 978-1-4899-1382-1 (eBook) DOI 10.1007/978-1-4899-1382-1 © 1996 Springer Science+Business Media New York Originally published by Plenum Press, New York in 1996 Softcover reprint of the hardcover 1st edition 1996

1098765432 1 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher

39TH OHOLO CONFERENCE Eliat, Israel, May 7-11, 1995

SCIENTIFIC ORGANIZING COMMITTEE Avigdor Shaffennan Sara Cohen MosheWhite Shaul Reuveny Baruch Velan

Israel Institute for Biological Research, Ness-Ziona, Israel Institute for Biological Research, Ness-Ziona, Israel Institute for Biological Research, Ness-Ziona, Israel Institute for Biological Research, Ness-Ziona, Israel Institute for Biological Research, Ness-Ziona,

Israel Israel Israel Israel Israel

SCIENTIFIC AD