Nutrition, Exercise and Epigenetics: Ageing Interventions
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by thes
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Byung Pal Yu Editor
Nutrition, Exercise and Epigenetics: Ageing Interventions
Healthy Ageing and Longevity Volume 2
Series editor Suresh I.S. Rattan, Aarhus, Denmark
More information about this series at http://www.springer.com/series/13277
Byung Pal Yu Editor
Nutrition, Exercise and Epigenetics: Ageing Interventions
123
Editor Byung Pal Yu Physiology University of Texas Health Science Center San Antonio, TX USA
ISSN 2199-9007 Healthy Ageing and Longevity ISBN 978-3-319-14829-8 DOI 10.1007/978-3-319-14830-4
ISSN 2199-9015 (electronic) ISBN 978-3-319-14830-4
(eBook)
Library of Congress Control Number: 2014960341 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 Chapter 2 was created within the capacity of an US governmental employment. US copyright protection does not apply. This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Preface
Achieving healthy longevity is an innate desire of humans and the ultimate goal of aging research endeavors. Aging intervention, popularly called “anti-aging” refers to slowing down the progress of aging and the accompanying disease processes. Many modern antiaging studies have attempted to uncover clues into the underlying mechanisms of aging or a means by which to manipulate genes and gene regulation of experimental organisms in effort to modulate the aging process. The past several decades’ work has made clear that searches for any genetic or gene manipulation or for aging genes, in particular, have produced disappointing results. This failure is neither unexpected nor surprising in view of our limited understanding of the precise functional genomic involvement in aging processes. Investigations of various other means of aging interventions, like dietary supplements, antioxidants, hormones, and pharmacologic agents, have also produced only
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