Nutritional assessment and surgical outcomes in very elderly patients undergoing pancreaticoduodenectomy: a retrospectiv
- PDF / 698,497 Bytes
- 13 Pages / 595.276 x 790.866 pts Page_size
- 60 Downloads / 221 Views
ORIGINAL ARTICLE
Nutritional assessment and surgical outcomes in very elderly patients undergoing pancreaticoduodenectomy: a retrospective study Masashi Utsumi1 · Hideki Aoki1 · Seiichi Nagahisa1 · Yuta Une1 · Yuji Kimura1 · Megumi Watanabe1 · Fumitaka Taniguchi1 · Takashi Arata1 · Koh Katsuda1 · Kohji Tanakaya1 Received: 17 July 2020 / Accepted: 29 September 2020 © Springer Nature Singapore Pte Ltd. 2020
Abstract Purpose To evaluate and compare the nutritional factors and clinical outcomes of pancreaticoduodenectomy between elderly and non-elderly patients. Methods This retrospective study evaluated 122 consecutive patients who underwent pancreaticoduodenectomy from April 2008 to April 2020. Preoperative and postoperative nutritional factors (prognostic nutritional index), complication rates, and survival rates were compared between the elderly (≥ 80 years) and non-elderly ( 80 years is increasing globally, accounting for approximately 1% of the total population, and it is predicted to increase four-fold by 2050 * Masashi Utsumi [email protected] 1
Department of Surgery, National Hospital Organization, Iwakuni Clinical Center, 1‑1‑1 Atago‑machi, Iwakuni‑shi, Yamaguchi 740‑8510, Japan
[7]. There will be an increasing need to consider patients older than 80 years of age for PD, particularly for the treatment of pancreatic cancer, for which the incidence increases with age [7]. The outcomes of PD have improved with better surgical techniques and postoperative care of patients [7]. However, performing this surgery in elderly patients is still a controversial issue. In many studies regarding PD, the elderly cohort accounted for a very small proportion of the study population. There may be some selection bias for the indication of PD. Compared to non-elderly patients, elderly patients are usually frail and malnourished and have more common diseases. The morbidity and mortality after PD are associated with malnutrition. Nutritional support may reduce postoperative complications in patients undergoing PD [8]. A low preoperative albumin level has been associated with an increased risk of morbidity and mortality in patients undergoing PD [9]. The prognostic nutritional index (PNI) and
13
Vol.:(0123456789)
Surgery Today
platelet-to-lymphocyte ratio are useful prognostic indicators for pancreatic cancer patients after PD [10]. However, the association between an elderly age and the nutrition status is unclear during the perioperative period. There exist few reports on the postoperative changes in the nutritional indexes in elderly patients. This study aimed to evaluate and compare the nutritional factors and clinical outcomes of PD between elderly (age ≥ 80 years) and non-elderly (age
Data Loading...
