Origin and Evolution of the Vertebrate Immune System
The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what
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Editors R.W. Compans, Atlanta/Georgia M. Cooper, Birmingham/Alabama J.M. Hogle, Boston/Massachusetts· Y. Ito, Kyoto H. Koprowski, Philadelphia/Pennsylvania· F. Melchers, Basel M. Old stone, La Jolla/California· S. Olsnes, Oslo M. Potter, Bethesda/Maryland· H. Saedler, Cologne P.K. Vogt, La Jolla/California· H. Wagner, Munich
Springer Berlin Heidelberg New York Barcelona Hong Kong Lotfdon Milan Paris Singapore Tokyo
Origin and Evolution of the Vertebrate Immune System Edited by L. Du Pasquier and G.W. Litman
With 81 Figures and 17 Tables
Springer
Professor Dr. LOUIS Du PASQUIER Basel Institute for Immunlogy Grenzacherstr. 487 CH-4005 Basel Switzerland e-mail: [email protected] Professor GARY W. LITMAN, M.D. University of South Florida All Children's Hospital 801 6th Street South St. Petersburg, FL 33701 USA e-mail: [email protected] Cover Illustration: Sometimes during his trip across Persia, Alexander the Great encollntered a wonder/iii talking tree with the heads of all sorts 0( l'ertabrat~s, The editors of Ihis volume hope that this "phylogenetic" tree will a/so talk 10 us allli bring n]essages of truth concerning the immune system. (Hand colored copy of a persian miniature, found in Delhi dllring the 10th 111lernatiOlwi Immunology Meeting, and representing the wonderful talking tree of Alexander)
ISSN 0070-217X e- ISBN -13 :978-3-642-59674-2 ISBN -13:978-3-642-64078-0 DOl: 10.10071978-3-642-59674-2
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Preface
The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates wa