Osteosarcopenia: Bone, Muscle and Fat Interactions
This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic
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Osteosarcopenia: Bone, Muscle and Fat Interactions
Osteosarcopenia: Bone, Muscle and Fat Interactions
Gustavo Duque Editor
Osteosarcopenia: Bone, Muscle and Fat Interactions
Editor Gustavo Duque Australian Institute for Musculoskeletal Science (AIMSS) The University of Melbourne and Western Health St. Albans, VIC, Australia Department of Medicine-Western Health Melbourne Medical School, The University of Melbourne St. Albans, VIC, Australia
ISBN 978-3-030-25889-4 ISBN 978-3-030-25890-0 (eBook) https://doi.org/10.1007/978-3-030-25890-0 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG. The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
In memory of my father, Maximo Duque, physicist and mathematician, an outstanding educator, and a role model who always inculcated in me the humility to respect the feeble, the curiosity to understand nature, and the respect for God who is the Great Architect of everything that is described in this book.
Foreword
Osteoporosis and sarcopenia are age-related musculoskeletal disorders which can have devastating impacts on both individuals and wider society. With an aging population, both conditions are likely to become increasingly prevalent in future decades, increasing the incidence of fragility fractures and leading to ever-greater morbidity, mortality, and socioeconomic cost. The notion that these two disorders might share epidemiologic, clinical, pathophysiologic, and therapeutic characteristics has grown over recent years. The term osteosarcopenia was coined to emphasize the coexistence of these two musculoskeletal disorders in individuals, and evidence regarding their cause, diagnosis, and treatment is elegantly covered in this volume. A clear understanding o
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