Ovarian Cancer in Elderly Patients

This practical book provides up-to-date information on the particular features of ovarian cancer in older women and the best management approach. The full range of relevant topics is covered. Guidance is provided on geriatric assessment, screening, pathol

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Ovarian Cancer in Elderly Patients

123

Ovarian Cancer in Elderly Patients

Gilles Freyer Editor

Ovarian Cancer in Elderly Patients

Editor Gilles Freyer HCL Cancer Institute Medical Oncology, and Université de Lyon Lyon

France

ISBN 978-3-319-23587-5 ISBN 978-3-319-23588-2 DOI 10.1007/978-3-319-23588-2

(eBook)

Library of Congress Control Number: 2015954241 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

Preface

This practical book provides up-to-date information on the particular features of ovarian cancer in older women and the best management approach. Various relevant topics are covered. Guidance is provided on geriatric assessment, pathology, molecular biology, diagnosis, and treatment. The various treatment options are carefully explained, covering surgical approaches, chemotherapy as a first-line strategy, use of anti-angiogenic agents, and treatment of relapse. The cognitive problems that may arise in elderly women during and after treatment of ovarian cancer are documented, with advice on response. Guidance is also provided on the design of clinical trials, and current directions in biological research are reviewed. This book will be of value to both practitioners and researchers with an interest in ovarian cancer and the elderly.

Lyon, France

Gilles Freyer, MD, PhD

v

Contents

1

Systemic Treatment of Cancer in the Older-Aged Person . . . . . . . . . Lodovico Balducci

2

Cognitive Function During and After Treatment in Elderly Ovarian Cancer Patients . . . . . . . . . . . . . . . . . . . . . . . . . . . Marie Lange and Florence Joly

3

Histopathology of Ovarian Cancers in Elderly Patients . . . . . . . . . . Mojgan Devouassoux-Shisheboran

4

Care of the Elderly Ovarian Cancer Patient: The Surgical Challenge .