Pain Comorbidities: Understanding and Treating the Complex Patient
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BOOK AND NEW MEDIA REVIEWS
Pain Comorbidities: Understanding and Treating the Complex Patient Maria Adele Giamberardino, Troels Staehelin Jensen. IASP Press, Seattle, WA, Year of Publication: 2012; Number of pages: 507; ISBN 978-0-931092-92-3 Akilan Velayudhan, MBBS
Received: 11 December 2012 / Accepted: 18 December 2012 / Published online: 4 January 2013 Ó Canadian Anesthesiologists’ Society 2013
This publication by IASP Press provides readers with a comprehensive update on chronic pain and its multiple interactions with medical comorbidities. The editors are leading experts in complex pain states, such as neuropathic pain, fibromyalgia, and headache, and the contributing authors have a range of expertise that spans from basic science research to clinical aspects of pain, including related physiotherapy and psychology considerations. The 41 contributing authors are based in Europe, North America, and Australia, and all are international experts on the topics presented in this publication. The authors review various clinical conditions to provide an understanding of the interactions of these conditions with multiple concurrent diseases and to offer guidance for their management. The book is divided into three parts. The focus of Part I is on the general aspects of pain, including epidemiology, and includes an introduction to various animal and human models of pain and non-pain comorbidities. Part II is a review of the clinical aspects of concurrent pain and nonpain conditions, and Part III involves management aspects of pain and non-pain comorbidities. The introductory section of the book provides background on some historical aspects of pain and includes a discussion on the important relationship between pain and emotions. This section also includes an overview of epidemiological approaches to measure the relationship between chronic pain and non-pain comorbidities. The discussion then extends to experimental animal models of pain and non-pain comorbidities and the possible clinical implications of translating research findings to clinical practice. The following chapter on experimental human A. Velayudhan, MBBS (&) University of Western Ontario, London, ON, Canada e-mail: [email protected]
models addresses the fundamentals of human quantitative pain assessment and their application in a variety of nonpainful disorders. The focus then turns to the neurobiological approach to comorbid pain conditions with evidence from animal models, genetic factors, hormonal factors, immunological factors, and psychosocial factors. Some of these topics may appeal to researchers as well as to clinicians interested in these areas. Part II of the book is rather intriguing as it involves clinical aspects of pain and non-pain comorbidities such as hypertension, diabetes, obesity, and metabolic and inflammatory disease. Two well-discussed issues in this section are the alteration of blood pressure-related hypoalgesia in chronic pain patients and the question whether or not chronic pain is a risk factor in the development of hyper
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