Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between
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Ellen Hsu Louis Du Pasquier Editors
Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
Results and Problems in Cell Differentiation
Volume 57
Series editors Dietmar Richter Henri Tiedge
More information about this series at http://www.springer.com/series/400
Ellen Hsu • Louis Du Pasquier Editors
Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations
Editors Ellen Hsu Department of Physiology and Pharmacology SUNY Downstate Medical Center Brooklyn, New York USA
Series Editors Dietmar Richter Center for Molecular Neurobiology University Medical Center Hamburg-Eppendorf (UKE) University of Hamburg Hamburg Germany
Louis Du Pasquier Institute of Zoology and Evolutionary Biology University of Basel Basel, Switzerland
Henri Tiedge The Robert F. Furchgott Center for Neural and Behavioral Science Department of Physiology and Pharmacology Department of Neurology SUNY Health Science Center at Brooklyn Brooklyn, New York USA
ISSN 0080-1844 ISSN 1861-0412 (electronic) Results and Problems in Cell Differentiation ISBN 978-3-319-20818-3 ISBN 978-3-319-20819-0 (eBook) DOI 10.1007/978-3-319-20819-0 Library of Congress Control Number: 2015955263 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Preface
Cre´er, c’est recombiner.—Franc¸ois Jacob
As changes over time—evolution—may be called adaptation at the species level, we refer to somatic adaptations as those genetic changes occurring in an animal’s cells during its lifetime. The latter phenomenon, with which this volume is concerned, deals with the genetic diversity generated in vegetative cells of individuals, whether parasite or host, enabling individualized responses for survival. This strategy allows members of the population to survive, procreat
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