Patients with Modic type 2 change have a severe radiographic representation in the process of lumbar degeneration: a ret
- PDF / 1,269,896 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 40 Downloads / 142 Views
(2019) 14:298
RESEARCH ARTICLE
Open Access
Patients with Modic type 2 change have a severe radiographic representation in the process of lumbar degeneration: a retrospective imaging study Mindong Lan1†, Yufu Ou2†, Chenglong Wang2†, Wei Wei1, Xianwei Lu1, Jianxun Wei2 and Xiaoping Mu2*
Abstract Background: There are few studies to investigate changes in imaging parameters of Modic changes (MCs). The imaging studies examining the distinctions in the lumbar sagittal parameters between MCs and lumbar disc degeneration (LDD) are still lacking. The purpose of this study was to identify the differences in the lumbar sagittal parameters among patients for LDD with/without Modic type 2 change (MII). Methods: A total of 208 patients with lumbar degenerative disease from January 2017 to August 2018 volunteered for this study. Sixty-two patients with MII were used as the MC group. The other 146 patients served as the disc degeneration (DD) group. The DD scores and sagittal parameters were measured on magnetic resonance imaging (MRI) and X-ray by using Surgimap software. Results: The prevalence of MII for patients with degenerative lumbar diseases in this study was 29.81%, primarily located at L5/S1. There were significant differences in lumbar lordosis (LL) and sacral slope (SS) between these two groups (P < 0.05). Similarly, the significant decrease in intervertebral height index (IHI) was found at L3-S1 in the MC group, compared with the DD group (P < 0.05). However, a significant difference in intervertebral angle (IVA) was observed only at L5/S1 (P < 0.05). The MC group had the smaller endplate concave angle (ECA) than the DD group from L3 caudal endplate to S1 cranial endplate (P < 0.05). Conclusions: MII has a severe radiographic representation in the process of lumbar degeneration than patients without MII, and the overconcentration of load caused by the smaller LL, SS, and IVA may be a reasonable explanation to answer why MCs are more common at the L5/S1. Keywords: Endplate signal changes, Modic changes, Lumbar degeneration, Lumbar sagittal parameters
Introduction The endplates between vertebral bone and intervertebral disc are the important elements in the structures of the lumbar spine, which are composed of thin hyaline cartilage with an average thickness of 0.6 mm [1, 2]. The anatomical structure of the endplate determines its important biomechanical role in walking upright humans. With the development of medical imageology, vertebral endplate * Correspondence: [email protected] † Mindong Lan, Yufu Ou, and Chenglong Wang contributed equally to this work. 2 Department of Orthopaedics, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China Full list of author information is available at the end of the article
can be clearly observed on MRI. Subsequently, Modic et al. [3, 4] first described the classification and histological features of the vertebral endplate and its adjacent bone marrow signal changes. Currently, Modic changes (MCs) have been considered as an important feature of spinal deg
Data Loading...
