Pediatric Hypertension
This outstanding second edition amplifies and improves this premier text on hypertension in neonates, children, and adolescents. Previous chapters have been fully revised and new chapters have been added to cover important topics of recent interest, such
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CLINICAL HYPERTENSION AND VASCULAR D ISEASES WILLIAM B. WHITE, MD SERIES EDITOR
Pediatric Hypertension, Second Edition, edited by Joseph T. Flynn, MD, MS, Julie R. Ingelfinger, MD, and Ronald J. Portman, MD, 2011 Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, Second Edition, edited by William B. White, MD, 2007 Hypertension in the Elderly, edited by L. Michael Prisant, MD, 2005 Lower Extremity Arterial Disease, edited by Dennis G. Caralis, MD, PhD, MPH, and George L. Bakris, MD, 2005 Secondary Hypertension, Clinical Presentation, Diagnosis, and Treatment, edited by George A. Mansoor, MD, 2004 Pediatric Hypertension, edited by Ronald J. Portman, MD, Jonathan M. Sorof, MD, and Julie R. Ingelfinger, MD, 2004
PEDIATRIC HYPERTENSION Second Edition Edited by
JOSEPH T. FLYNN, MD, MS Division of Nephrology, Seattle Children’s Hospital, Seattle, WA, USA
JULIE R. INGELFINGER, MD Pediatric Nephrology Unit, Department of Pediatrics, Harvard Medical School and MassGeneral Hospital for Children at Massachusetts General Hospital, Boston, MA, USA
RONALD J. PORTMAN, MD Pediatric Drug Development Program, Bristol-Myers Squibb, Princeton, NJ, USA
Editors Joseph T. Flynn, MD, MS Division of Nephrology Seattle Children’s Hospital 4800 Sand Point Way NE Seattle, WA 98105, USA [email protected]
Julie R. Ingelfinger, MD Massachusetts General Hospital and Harvard Medical School 55 Fruit St. Boston, MA 02114, USA [email protected]
Ronald J. Portman, MD Bristol-Myers Squibb Global Clinical Research Route 206 & Provinceline Road Princeton, NJ 08543, USA
ISBN 978-1-60327-823-2 e-ISBN 978-1-60327-824-9 DOI 10.1007/978-1-60327-824-9 Springer New York Dordrecht Heidelberg London © Springer Science+Business Media, LLC 2004, 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is part of Springer Science+Business Media (www.springer.com)
Foreword While hypertension in children and adolescents has a significant impact on
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